3D打印技术联合术中电生理监测在桥脑小脑角肿瘤切除中的应用价值分析  

Value of 3D printing combined with intraoperative electrophysiological monitoring in excision of cerebellopontine angle tumor

作　　者：王国文 贺艳阳[1] 王博[1] 谢姗姗 靳腾龙 王亚周 邵冰水 高坤 李凯[1] 张敏丽 赵红宇[2] Wang Guowen;He Yanyang;Wang Bo;Xie Shanshan;Jin Tenglong;Wang Yazhou;Shao Bingshui;Gao Kun;Li Kai;Zhang Minli;Zhao Hongyu(Department of Neurosurgery,People's Hospital of Zhengzhou,Zhengzhou 450003,China;Department of Neurosurgery,Shengjing Hospital of China Medical University,Shenyang 110134,China)

机构地区：[1]郑州人民医院神经外科,450003 [2]中国医科大学附属盛京医院神经外科,沈阳110134

出　　处：《中华神经医学杂志》2021年第7期700-704,共5页Chinese Journal of Neuromedicine

基　　金：河南省医学科技攻关计划项目(2018020815、LHGJ20191070)。

摘　　要：目的探讨3D打印技术联合术中电生理监测在桥脑小脑角(CPA)肿瘤切除中的应用价值。方法收集并分析郑州人民医院神经外科自2016年10月至2019年10月手术治疗的43例CPA肿瘤患者的临床资料。按照手术方式的不同分为2组,普通组(27例)行普通显微切除术,优化组(16例)行术前3D打印技术联合术中电生理监测下显微切除术。统计分析2组患者的肿瘤切除程度和神经功能(面听神经功能、吞咽功能、肢体活动)改善情况,比较其手术疗效。结果优化组患者的肿瘤切除程度、面听神经功能改善优于普通组,差异均有统计学意义(P<0.05);2组患者的吞咽功能、肢体活动改善程度比较,差异均无统计学意义(P>0.05)。结论3D打印技术联合术中电生理监测能够提高CPA肿瘤切除率并保护面听神经,改善患者术后生活质量。Objective To investigate the value of 3D printing combined with intraoperative electrophysiological monitoring in excision of cerebellopontine angle(CPA)tumor.Methods The clinical data of 43 patients with CPA tumor,admitted to our hospital from October 2016 to October 2019,were collected and analyzed.These patients were voluntarily divided into ordinary group(n=27)and optimized group(n=16).Patients in the ordinary group were operated microscopically,and those in the optimized group were operated microscopically with 3D printing combined with intraoperative electrophysiological monitoring.The degrees of tumor resection and neurological functions(facial and auditory nerve function,swallowing function,limb activity)improvements were compared between the two groups.Results The degrees of tumor resection of the optimized group were significantly higher than those of the ordinary group(P<0.05),and the improvement of facial and auditory nerve function in the optimized group was significantly better than that in the ordinary group(P<0.05).There was no significant difference in improvements of swallowing function and limb activity between the two groups(P>0.05).Conclusion The 3D printing combined with intraoperative electrophysiological monitoring can improve the resection rate of CPA tumor,protect the facial auditory nerve,and improve the quality of life of patients after surgery.

关 键 词：桥脑小脑角 脑肿瘤 3D打印技术 术中电生理监测 

分 类 号：R739.41[医药卫生—肿瘤]