Visible Light-Promoted Sulfoxonium Ylides Synthesis from Aryl Diazoacetates and Sulfoxides  

作　　者：Juan Lu Lei Li Xiang-Kui He Guo-Yong Xu Jun Xuan 

机构地区：[1]Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials,College of Chemistry&Chemical Engineering,Anhui University,Hefei,Anhui 230601,China [2]Key Laboratory of Structure and Functional Regulation of Hybrid Materials(Anhui University),Ministry of Education,Hefei,Anhui 230601 China [3]Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province,School of Science,Westlake University,18 Shilongshan Road,Hangzhou,Zhejiang 310024,China [4]Institute of Physical Science and Information Technology,Anhui University,Hefei,Anhui 230601,China

出　　处：《Chinese Journal of Chemistry》2021年第6期1646-1650,共5页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(Nos.21971001 and 21702001);the Natural Science Foundation of Anhui Province(No.1808085MB47);the Open Fund for Discipline Construction,Institute of Physical Science and Information Technology,Anhui University,and the Start-Up Grant from Anhui University for financial support of this work.

摘　　要：A visible light-promoted reaction of donor/acceptor diazoalkanes with sulfoxides towards the synthesis of synthetically useful sulfoxonium ylides was reported.The reaction occurred under sole visible light irradiation without the need of any transition-metals or additives,affording the corresponding sulfoxonium ylides in moderate to good yields.The success of late-stage modification of natural isolates or drug candidates,scale-up reaction and transformation of sulfoxonium ylides to other useful molecules further rendered the approach valuable.

关 键 词：Sulfoxonium ylides Synthetic methods CARBENE Visible Light Diazo compounds 

分 类 号：O62[理学—有机化学]