Cobalt-Catalyzed C-H Allylation of Arenes with Allylic Amines  

作　　者：Rui Yan Hang Yu Zhong-Xia Wang 

机构地区：[1]CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry,University of Science and Technology of China,Hefei,Anhui 230026,China [2]Colloborotive Innovation Center of Chemical Science and Engineering,Tianjin 300072,China

出　　处：《Chinese Journal of Chemistry》2021年第5期1205-1210,共6页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(No.21372212);the National Basic Research Program of China(No.2015CB856600)is greatly acknowledged.

摘　　要：[Cp^(*)Co(CO)l_(2)]effectively catalyzes pyridyl-directed C-H allylation of arenes with allylic amines in the presence of AgOAc and CF_(3)COOAg.The reaction features ortho-position monoallylation of 2-pyridylarenes,giving the allylated arenes in moderate to high yields.A range of functional groups including OMe,Me,Ph,F,Cl,Br,CF_(3),C(0)Me,COOEt,and COOH groups are tolerated.Pyrim-idyl-directed C-H allylation of arenes were also performed under the same conditions.Reaction of 2-phenylpyrimidine,2-(4-methoxyphenyl)pyrimidine/and 2-(3-fluorophenyl)pyrimidine leads to a mixture of ortho-position mono-and bisallylation products.Reaction of other 2-(substituted aryl)pyrimidines resulted in ortho-position monoallylation products.

关 键 词：C-H activation C-N activation Homogeneous catalysis Cobalt catalysis ALLYLATION 

分 类 号：O62[理学—有机化学]