Financial support was provided by the National Natural Science Foundation of China(22337005,22277133,91753126);Youth Innovation Promotion Association CAs(2023266);CAS Interdisciplinary Innovation Team(JCTD-2020-16);Program of Shanghai Academic/Technology Research Leader(21XD1424700);International Partnership Program of the Chinese Academy of Science(033GJHZ2023006FN).
Enhancing the DNA toolbox with innovative photochemical reactions is pivotal for advancing nucleic acid-based technologies.Aldehyde groups,versatile bioorthogonal handles for imine formation under acidic conditions,ar...
the National Natural Science Foundation of China (22171099, and 92256301);the National Key R&D Program of China (2023YFA1507203 and 2022YFA1506100);the Open Research Fund of School of Chemistry and Chemical Engineering;the Fundamental Research Funds for the Central Universities of China (CCNU24JCPT016);Henan Normal University (2021YB02);the Double-Thousand Talents Plan of Jiangxi Province (jxsq2023102004)。
Radical-involved allylation reactions have emerged as a powerful platform for construction of carbon-carbon and carbonheteroatom bonds, facilitating the strategic incorporation of diverse allyl moieties. Nevertheless,...
the National Key R&D Program of China(grant nos.2023YFA1506700,2022YFA1503702,and 2021YFF0701602);National Natural Science Foundation of China(NSFC,grant nos.22231011 and 22271303);Shanghai Scientific and Technological Innovation Project,China(grant no.22JC1401000).
A synergistic Pd/Zn dual chiral catalyst system has been developed for the stereodivergent transformation of Morita–Baylis–Hillman(MBH)carbonates and unprotectedα-hydroxyketones to afford the corresponding allylati...
supported by the Natural Science Foundation of Shandong Province(ZR2019BB011);the Scientific Research Foundation of Qingdao University of Science&Technology(010029022).
A Ru(II)-catalyzed ortho allylation reaction of N-aryl-7-azaindole with readily available 2-methylidene cyclic carbonate has been developed.This reaction is an effective pathway for synthesizing 7-azaindole derivative...
financial supports from the National Key R&D Program of China(grant nos.2022YFA1503702 and 2021YFF0701602);NSFC(grant nos.22231011 and 22271303).
Oxazolones are structural subunits in numerous natural products and designed molecules with substantial pharmacological properties.Here,a palladium-catalyzed chemodivergent regio-and enantioselective allylic alkylatio...
supported by the National Natural Science Foundation of China(No.22201300);the Fundamental Research Funds for the Central Universities,and the Research Funds of Renmin University of China(No.21XNLG04).
We have summarized the developments and advancements of allyl-(aza)allyl coupling reactions in the past years.Since the first report in 1980,Pd-catalyzed allyl-allyl couplings have not drawn chemists'much attention fo...
the National Key R&D Program of China(2021YFA1500100);Youth Innovation Promotion Association CAS(2020448);NSFC(22171254 and 22188101);Anhui Provincial Natural Science Foundation(2108085MB58);USTC Research Funds of the DoubleFirst-Class Initiative(YD2060002024);Start-up Research Fund from University of Science and Technology of China(KY2060000216).
Comprehensive Summary Pd-catalyzed asymmetric allylic C—H functionalization has emerged as a powerful tool to access chiral,densely functionalized molecules from easily accessible alkenes,enabling the increase of the...
financial support from the National Natural Science Foundation of China(No.21602144);the Science and Technology Program of Sichuan Province(No.2018JY0485);Scientific Research Project of Education Department of Hubei Province(Nos.Q20211503,B2020057)。
The utilization of readily available amino acids,which is not only an oxygen nucleophile but also a nitrogen nucleophile,in palladium-catalyzed allylic substitution is realized under mild conditions.The chemoselectivi...
the National Natural Science Foundation of China(Grants 22025104,21972064 and 21901111);the Fundamental Research Funds for the Central Universities for their financial support(Grant 020514380254);The project was also supported by Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University.
Monofluoroalkenes are important and versatile privileged components in pharmacologically relevant molecules.Here,we report a method for the selective construction of these compounds in a diversity-oriented fashion thr...
This work is supported by the National Natural Science Foundation of China(No.21890723);Sichuan University(2020SCUNL204).
Comprehensive Summary Asymmetric catalytic allylation of halo-substituted ketones and ketoesters was accomplished to yield a number of homoallylic tertiary alcohols in excellent reactivity and enantioselectivity.In th...