基于CT肝癌3D slicer人工智能建模精准辅助外科的应用研究  

Application of CT-based 3D Slicer Artificial Intelligence Modeling of Liver Cancer in Precision Assisted Surgery

作　　者：吴兆平[1] 彭浪 金煜东 陈伟力[1] WU Zhaoping;PENG Lang;JIN Yudong;CHEN Weili(Jiujiang NO.1 People’s Hospital,Jiujiang 332000,China;不详)

机构地区：[1]江西省九江市第一人民医院,江西九江332000

出　　处：《中国医学创新》2021年第18期5-9,共5页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(SKJP202140279)。

摘　　要：目的:探讨基于电子计算机断层扫描(computed tomography,CT)肝癌三维切片(three dimensional slicer,3D slicer)人工智能(artificial intelligence,AI)建模精准辅助外科的应用效果。方法:选择2018年6月-2020年9月本院收诊的60例肝癌患者,均行腹腔镜肝切除术。按照有无辅助应用基于CT的3D slicer AI建模分为试验组(n=30,应用)与对照组(n=30,未应用)。观察两组手术出血量、肝门阻断时间、手术时间,分析两组术后7 d前白蛋白(prealbumin,PAB)、白蛋白(albumin,ALB)、转铁蛋白(transferrin,TRF)水平,比较其术后7 d静息能量消耗(resting energy expenditure,REE)水平、分化簇4(cluster of differentiation 4,CD4^(+))/分化簇8(cluster of differentiation 8,CD8^(+)),且需统计其转开腹率、术后7 d并发症发生率及围手术期死亡率。结果:试验组手术出血量较对照组少,肝门阻断时间、手术时间均较对照组短,差异均有统计学意义(P<0.05)。两组术后7 d PAB、ALB、TRF、CD4^(+)/CD8^(+)水平均较术前降低,但试验组均较对照组高,差异均有统计学意义(P<0.05);而其术后7 d REE水平较术前升高,但试验组较对照组低,差异均有统计学意义(P<0.05)。试验组转开腹率、围手术期间死亡率与对照组相比,差异均无统计学意义(P>0.05)。试验组并发症发生率较对照组低,差异有统计学意义(P<0.05)。结论:基于CT的3D slicer AI建模辅助肝癌患者完成腹腔镜肝切除术,有助于减少患者的手术时间、手术出血量与并发症情况,可促使患者的血清内脏蛋白水平尽早恢复正常,且能够改善其能量代谢与免疫功能。Objective:To explore the application effect of artificial intelligence(AI)modeling based on computed tomography(CT)three-dimensional slicer(3D slicer)of liver cancer in precision assisted surgery.Method:Sixty patients with liver cancer admitted to our hospital from June 2018 and September 2020 were selected for laparoscopic hepatectomy.According to whether the 3D slicer AI modeling based on CT was used as auxiliary application,the patients were divided into the experimental group(n=30,used)and the control group(n=30,not used).The surgical blood loss,hepatic portal occlusion time and surgical time were observed in two groups,and the levels of prealbumin(PAB),albumin(ALB)and transferrin(TRF)of two groups were analyzed at 7 d after surgery.The resting energy expenditure(REE)and cluster of differentiation 4(CD4^(+))/cluster of differentiation 8(CD8^(+))were compared at 7 d after surgery.The rate of conversion to laparotomy,total rate of complications at 7 d after surgery and perioperative mortality rate were statistically analyzed.Result:The surgical blood loss in the experimental group was less than that in the control group,and the hepatic portal occlusion time and surgical time were shorter than those in the control group(P<0.05).The levels of PAB,ALB,TRF and CD4^(+)/CD8^(+)at 7 d after surgery in the two groups were decreased compared with those before surgery,and the levels in the experimental group were higher than those in the control group(P<0.05).The REE level at 7 d after surgery was increased compared to before surgery,and the level in the experimental group was lower than that in the control group(P<0.05).There were no significant differences in the rate of conversion to laparotomy and mortality rate during the perioperative period in the experimental group compared to the control group(P>0.05).The incidence rate of complications of the experimental group was lower than that of the control group(P<0.05).Conclusion:CT-based 3D slicer AI modeling assists patients with liver cancer to complete laparoscopic h

关 键 词：肝癌 CT 3Dslicer 外科手术 人工智能建模 

分 类 号：R735.7[医药卫生—肿瘤]