近10年延边地区上消化道出血的临床特征分析  

Analysis of clinical characteristics of upper gastrointestinal bleeding in Yanbian area in recent 10 years

作　　者：张佳慧 黄媛[1] 金海燕[1] ZHANG Jiahui;HUANG Yuan;JIN Haiyan(Department of Gastroenterology and Hepatology,Affiliated Hospital of Yanbian University,Yanji 133000,Jilin,China)

机构地区：[1]延边大学附属医院消化内科,吉林延吉133000

出　　处：《延边大学医学学报》2021年第1期49-52,共4页Journal of Medical Science Yanbian University

摘　　要：[背景]回顾性分析近10年延边地区上消化道出血(UGIB)的临床特征.[病例报告]收集2010年1月1日至2019年12月31日UGIB住院并行胃镜检查的1 943例患者的资料进行分析.结果见,UGIB住院患者的年镜检率呈增高趋势(P<0.001).UGIB的前4位病因是消化性溃疡(42.2%)、食管胃底静脉曲张(33.3%)、急性胃黏膜病变(11.5%)及恶性肿瘤(5.4%).服药后出血的患者中服用非甾体类抗炎药物者在2010—2014年占77.5%,2015—2019年占89.0%.2010—2014年与2015—2019年比较,急性胃黏膜病变患者呈增加趋势;朝鲜族由56.4%下降到51.6%,汉族由42.5%上升到46.7%(P=0.039);出血的平均年龄由(58.34±13.11)岁升高到(59.54±13.45)岁(P=0.049).秋冬季消化性溃疡和食管胃底曲张静脉出血人数明显多于春夏季(P<0.001).[讨论]近10年间UGIB年镜检率呈递增趋势,UGIB的前4位病因为消化性溃疡、食管胃底静脉曲张、急性胃黏膜病变和恶性肿瘤,主要诱因是服用非甾体类抗炎药物,并与年龄、民族和季节相关.BACKGROUND To analyze the clinical characteristics of upper gastrointestinal bleeding(UGIB) in Yanbian area in recent 10 years. CASE REPORTS The data of 1 943 patients hospitalized for UGIB and underwent gastroscopy from January 1, 2010 to December 31, 2019 were collected. The results showed that annual gastroscopic examination rate of hospitalized patients with UGIB was increasing(P<0.001). The top 4 causes of UGIB were peptic ulcer(42.2%), esophageal gastric fundus varices(33.3%), acute gastric mucosal lesion(11.5%) and malignant tumor(5.4%). Among the patients with UGIB after medication, NSAIDs accounted for 77.5% from 2010 to 2014 and 89.0% from 2015 to 2019. Compared with 2015 to 2019, the number of patients with acute gastric mucosal lesions increased, the number of UGIB decreased from 56.4% to 51.6% in Korean nationality, while increased from 42.5% to 46.7% in Han nationality(P=0.039), the average age of UGIB increased from(58.34±13.11) years old to(59.54±13.45) years old(P=0.049) from 2010 to 2014. The number of peptic ulcer and esophageal gastric fundus variceal bleeding in autumn and winter was more than that in spring and summer(P<0.001). DISCUSSION In recent 10 years, the annual gastroscopic examination rate of UGIB showed an increasing trend. The top 4 causes of gastrointestinal bleeding are peptic ulcer, esophageal gastric fundus varices, acute gastric mucosal lesions and malignant tumors. The main inducer of UGIB is the use of NSAIDs, and related to age, nationality and season.

关 键 词：上消化道出血 病因 相关因素 

分 类 号：R573.2[医药卫生—消化系统]