甘孜州高原地区3~7岁儿童维生素D营养状况与龋齿发病率的相关性  

Correlation between vitamin D status and dental caries incidence rate in children aged 3-7 years in Ganzi Prefecture

作　　者：罗晶[1] 黄萍[1] 林新梅[2] 王全生 魏正蓉 巴学国 袁永潇 丁红燕 何茂云 李红梅[1] 徐义兰[1] 宋芳[1] 董清科 LUO Jing;HUANG Ping;LIN Xinmei;WANG Quansheng;WEI Zhengrong;BA Xueguo;YUAN Yongxiao;DING Hongyan;HE Maoyun;LI Hongmei;XU Yilan;SONG Fang;DONG Qingke(Department of Child Health Care,Luzhou People’s Hospital,Luzhou Sichuan 646000;Department of Blood Transfusion,Luzhou People’s Hospital,Luzhou Sichuan 646000;Department of Rehabilitation,Luxian Hospital of Traditional Chinese Medicine,Luzhou Sichuan 646100;Department of Pediatrics,People’s Hospital of Daocheng County,Ganzi Sichuan 627750;Department of Internal Medicine,People’s Hospital of Xiangcheng Ganzi Prefecture,Ganzi Sichuan 627185;Department of Oncology,Luzhou People’s Hospital,Luzhou Sichuan 646000,China)

机构地区：[1]泸州市人民医院儿童保健科,四川泸州646000 [2]泸州市人民医院输血科,四川泸州646000 [3]泸县中医医院康复科,四川泸州646100 [4]甘孜州稻城县人民医院儿科,四川甘孜627750 [5]甘孜州乡城县人民医院内科,四川甘孜627185 [6]泸州市人民医院肿瘤科,四川泸州646000

出　　处：《临床与病理杂志》2021年第7期1629-1633,共5页Journal of Clinical and Pathological Research

基　　金：四川省卫生与计划生育科研课题(17PJ277)。

摘　　要：目的:探讨四川省甘孜藏族自治州(以下简称甘孜州)高原地区3~7岁儿童维生素D[25-(OH)D]营养状况与龋齿发病率的关系。方法:2017年11月至2018年4月,选取四川省甘孜藏族自治州乡城县、稻城县3~7岁藏区儿童810名,检测血清25-(OH)D水平,调查儿童龋齿发生情况。结果:>6~7岁组龋齿发病率为57.44%,明显高于3~4岁组、>4~5岁组(P<0.05);>5~6岁组、>4~5岁组龋齿发病率为52.03%和43.68%,明显高于3~4岁组(P<0.05);>6~7岁组儿童血清25-(OH)D为(22.92±5.15)ng/mL,明显低于3~4岁组、>4~5岁组(P<0.05);>6~7岁组25-(OH)D缺乏或不足儿童龋齿发病率为62.34%,明显高于3~4岁组(P<0.05);>5~6岁组25-(OH)D缺乏或不足龋齿发病率为58.93%,明显高于3~4岁组(P<0.05)。结论:甘孜州高原地区3~7岁儿童龋齿、25-(OH)D缺乏或不足的比例较高,其中龋齿发生与25-(OH)D缺乏或不足有一定关系。Objective:To explore the relationship between vitamin D[25-(OH)D]nutrition status and dental caries incidence rate in 3-7 years old children in plateau area in Garzi Tibetan Autonomous Prefecture.Methods:From November 2017 to April 2018,810 children aged 3-7 in Xiangcheng County and Daocheng County of Ganzi Tibetan Autonomous Prefecture in Sichuan Province were selected to test the serum 25-(OH)D level and investigate the occurrence of dental caries in children.Results:The incidence rate of dental caries in the group aged from>6-7 years was 57.44%,which was significantly higher than that in the 3-4 years old group and>4-5 years old group(P<0.05).The incidence rates of dental caries in>5-6 years old group and>4-5 years old group were 52.03%and 43.68%,which were significantly higher than that in 3-4 years old group(P<0.05).The serum 25-(OH)D was(22.92±5.15)ng/mL in the>6-7 years old group,which was significantly lower than that in the 3-4 years old group and>4-5 years old group(P<0.05).The incidence rate of dental caries in>6-7 years old group was 62.34%,which was significantly higher than that in 3-4 years old group(P<0.05).The incidence rate of dental caries in 25-(OH)D deficiency or insufficiency in>5-6 years old group was 58.93%,which was significantly higher than that in 3-4 years old group(P<0.05).Conclusion:The prevalence of dental caries and 25-(OH)D deficiency or insufficiency are higher in 3-7 years old children in the plateau area of Ganzi Prefecture.There is a certain relationship between dental caries and 25-(OH)D deficiency or insufficiency.

关 键 词：高原地区 3~7岁儿童 维生素D 龋齿 

分 类 号：R788.1[医药卫生—口腔医学]