孕中期血清甲胎蛋白和游离β-人绒毛促性腺激素联合检测的价值分析  

The clinical significance of fetal chromosomal abnormalities and pregnancy outcome in prenatal screening with serum indicators in the second trimester

作　　者：宋莉[1] SONG Li(Department of Clinical Laboratory,Dazhou Hospital of Integrated Traditional Chinese and Western Medicine,Dazhou,Sichuan 635000,China)

机构地区：[1]达州市中西医结合医院检验科,四川达州635000

出　　处：《医药前沿》2021年第18期10-11,共2页Journal of Frontiers of Medicine

摘　　要：目的:分析孕中期血清甲胎蛋白和游离β-人绒毛促性腺激素联合检测的价值。方法:选取2019年7月—2020年8月我院进行产前筛查的孕妇3500例,对所有孕妇都进行甲胎蛋白(AFP)、游离β-人绒毛促性腺激素(free-β-HCG)二联血清检测,对检测结果MOM值及妊娠结局进行分析。结果:MOM值异常孕妇124例,高风险孕妇284例,且MOM值异常、高风险和预产年龄≥35岁高风险孕妇出现不良妊娠结局的概率要高于MOM值正常、低风险和预产年龄<35岁高风险孕妇,差异有统计学意义(P<0.05)。结论:孕中期血清甲胎蛋白和游离β-人绒毛促性腺激素联合检测在产前筛查的临床意义显著。Objective To analyze the clinical significance of fetal chromosomal abnormalities and pregnancy outcome in prenatal screening with serum indicators in the second trimester.Methods Select 3,500 pregnant women who came to our hospital for prenatal screening between July 2019 and August 2020.All pregnant women were given alpha-fetoprotein(AFP)and freeβ-human chorionic gonadotropin(free-β-HCG).Dual serum test to analyze test results and pregnancy outcome.Results There were 124 pregnant women with abnormal MOM,284 high-risk pregnant women,and abnormal MOM,high-risk and expected delivery age≥35 years old.High-risk pregnant women are more likely to have adverse pregnancy outcomes than normal MOM,low-risk and expected delivery age.A 35-year-old high-risk pregnant woman(P<0.05).Conclusion The clinical significance of fetal chromosomal abnormalities and pregnancy outcomes is significant in prenatal screening with serum indicators in the second trimester.

关 键 词：胎儿染色体异常 妊娠结局 孕中期血清指标 产前筛查 

分 类 号：R596.1[医药卫生—内科学]