内镜下切开术治疗难治性食管癌术后吻合口狭窄的疗效  

Effect of endoscopic incision method in the treatment of postoperative anastomotic stricture of refractory esophageal carcinoma

作　　者：强利敏 法卫玲 陈黎 蔡秋霞 QIANG Limin;FAWeiling;CHEN Li;CAI Qiuxia(Department of Thoracic Surgery,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,He’nan,China;Teaching Office,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,He’nan,China;Department of Pharmacy,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,He’nan,China)

机构地区：[1]郑州大学附属洛阳中心医院胸外科,河南洛阳4710000 [2]郑州大学附属洛阳中心医院教学办,河南洛阳4710000 [3]郑州大学附属洛阳中心医院药学部,河南洛阳4710000

出　　处：《癌症进展》2021年第13期1349-1351,1355,共4页Oncology Progress

摘　　要：目的探究食管支架置入术(ESP)和内镜下切开术(EIM)在难治性食管癌术后吻合口狭窄治疗中的应用效果。方法将70例难治性食管癌术后吻合口狭窄患者按照手术方式不同分为ESP组(n=41)与EIM组(n=29)。对比两组患者临床疗效、吞咽困难评分及并发症发生情况。结果两组患者总有效率比较,差异无统计学意义(P﹥0.05)。术前,两组患者Stooler评分比较,差异无统计学意义(P﹥0.05);术后1个月,两组患者Stooler评分均较术前降低(P﹤0.05),且EIM组患者Stooler评分明显低于ESP组(P﹤0.01)。ESP组患者术后并发症总发生率高于EIM组(P﹤0.05)。结论 EIM和ESP治疗难治性食管癌吻合口狭窄的临床疗效相当,EIM短期内对患者吞咽困难症状改善作用明显,且具有术后并发症少等优点。Objective To explore the effect of esophageal stent placement(ESP)and endoscopic incision method(EIM)in the treatment of postoperative anastomotic stricture of refractory esophageal carcinoma.Method A total of 70 patients with postoperative anastomotic stricture of refractory esophageal carcinoma were divided into the ESP group(n=41)and EIM group(n=29)according to different surgical methods,and the clinical efficacy,score of dysphagia and complications between the two groups were compared.Result There was no significant difference in the total effective rate between the two groups(P>0.05).There was no significant difference in Stooler score of dysphagia between the two groups before operation(P>0.05)versus lower Stooler scores one month after operation in both groups than those before operation(P<0.05)and lower score in the EIM group than that in the ESP group(P<0.01).The total incidence of postoperative complications in ESP group was higher than that in EIM group(P<0.05).Conclusion The clinical efficacy of EIM and ESP in the treatment of anastomotic stricture of refractory esophageal carcinoma is comparable,with significant improvement of dysphagia in a short time and less postoperative complications by the treatment of EIM.

关 键 词：食管支架置入术 内镜下切开术 难治性食管癌吻合口狭窄 吞咽困难 

分 类 号：R735.1[医药卫生—肿瘤]