肺癌化疗患者的化疗相关症状群与健康行为的相关性研究  

Correlation between chemotherapy-related symptom cluster and healthy behavior in patients with lung cancer chemotherapy

作　　者：方建瑞[1] 王艳荣[1] 于桂青[1] 张春燕[2] FANG Jianrui;WANG Yanrong;YU Guiqing;ZHANG Chunyan(Department of Respiratory Medicine,Nanyang Central Hospital,Nanyang 473009,He’nan,China;Department of Emergency,Anyang People’s Hospital,Anyang 455002,He’nan,China)

机构地区：[1]南阳市中心医院呼吸内科,河南南阳473009 [2]安阳市人民医院急诊科,河南安阳4550020

出　　处：《癌症进展》2021年第13期1382-1385,共4页Oncology Progress

摘　　要：目的探讨肺癌化疗患者的化疗相关症状群与健康行为的相关性。方法选取230例肺癌化疗患者,采用一般资料调查问卷、简易疲乏量表(BFI)、匹兹堡睡眠质量指数(PSQI)、数字评分法(NRS)、医院用焦虑抑郁量表(HADS)、健康促进生活方式量表Ⅱ(HPLPⅡ)对患者进行问卷调查,采用系统聚类中的指标聚类分析方法进行聚类分析,将BFI、PSQI、NRS和HADS评分相加评估化疗相关症状群的严重程度。结果 230例肺癌化疗患者的BFI评分为(2.89±0.73)分,PSQI评分为(5.09±1.48)分,HADS评分为(4.32±0.96)分,NRS评分为(2.45±0.63)分。肺癌化疗患者的化疗相关症状群主要表现为疲乏、睡眠障碍、焦虑、疼痛,肺癌化疗患者中重度化疗相关症状群85例(36.96%),轻度145例(63.04%)。230例肺癌化疗患者健康行为总分为(115.74±13.20)分,属于不健康的生活方式。Pearson相关分析结果显示,肺癌化疗患者的化疗相关症状群与HPLPⅡ各维度评分及总分间均呈负相关。结论肺癌化疗患者普遍存在化疗相关症状群,提高患者的健康行为水平有利于减轻患者的化疗相关症状群程度。Objective To investigate the correlation between chemotherapy-related symptom cluster and healthy behavior in patients with lung cancer chemotherapy.Method A total of 230 patients with lung cancer chemotherapy were selected.General information questionnaire,brief fatigue inventory(BFI),Pittsburgh sleep quality index(PSQI),numeric rating scale(NRS),hospital anxiety and depression scale(HADS),health promoting lifestyle profile II(HPLP II)were used to survey the subjects.The cluster analysis was performed using the index cluster analysis method belonging to the hierarchical clustering,the BFI,PSQI,NRS,and HADS scores were added together to assess the severity of chemotherapy-related symptom cluster.Result The average scores of 230 lung cancer chemotherapy patients’BFI,PSQI,HADS,NRS was(2.89±0.73)points,(5.09±1.48)points,(4.32±0.96)points,and(2.45±0.63)points,respectively.The primary chemotherapy-related symptoms of lung cancer chemotherapy patients were fatigue,sleep disturbance,anxiety,and pain.In lung cancer chemotherapy patients,85 cases(36.96%)of moderate to severe chemotherapy-related symptom cluster and 145 cases(63.04%)of mild events.The total health behavior score of 230 patients with lung cancer chemotherapy was(115.74±13.20)points,which was under the unhealthy lifestyle level.The Pearson correlation analysis results indicated a negative correlation between the chemotherapy-related symptom cluster of patients with lung cancer chemotherapy and the individual dimension scores and total scores of HPLP II.Conclusion Chemotherapy-related symptom cluster is common in patients with lung cancer chemotherapy.It brings great benefit to improving the patient’s health behavior which could alleviate the degree of the symptom cluster.

关 键 词：症状群 肺癌 化疗 健康行为 

分 类 号：R734.2[医药卫生—肿瘤]