基于包埋技术的小型猪心冠状动脉铸型三维建模及价值应用  

Three dimensional modeling and value application of coronary artery casting in miniature pig heart based on embedding technology

作　　者：郑二来[1] 陈金锋[1] 陈进军 黄海龙[1] 陈小宇 邓健全[1] ZHENG Erlai;CHEN Jinfeng;CHEN Jinjun;HUANG Hailong;CHEN Xiaoyu;DENG Jianquan(Ministry of Basic Medicine,Zhaoqing Medical College,Zhaoqing 526020,China;Department of Imaging,Zhaoqing Hospital of TCM,Zhaoqing 526020)

机构地区：[1]肇庆医学高等专科学校基础医学部,广东肇庆526020 [2]肇庆市中医院影像科,广东肇庆526020

出　　处：《中国比较医学杂志》2021年第7期44-48,共5页Chinese Journal of Comparative Medicine

基　　金：广东省医学科研基金项目(B2021408)。

摘　　要：目的探讨小型猪心冠状动脉解剖结构的立体构筑及其保存应用。方法选取5个完整的新鲜广西巴马小型猪心脏作为实验对象,经灌注、腐蚀等制作小型猪心冠状动脉铸型标本,并探索采用水晶滴胶包埋和三维重建技术构筑小型猪心冠状动脉铸型模型及其三维立体模型的制作流程。结果小型猪心冠状动脉铸型包埋模型透亮度高,可清晰观察到小型猪心冠状动脉血管走行及分支分布,并且无铸型支断落;其三维模型构筑了小型猪心冠状动脉解剖结构,立体感强,无伪影,可在三维空间内任意角度旋转及分割。结论水晶包埋铸型模型可以有效地保护小型猪心冠状动脉铸型标本,其三维模型也可为动物模型的血管三维虚拟仿真研究提供技术及经验基础。Objective This study aimed to investigate the stereoscopic structure of the coronary artery in miniature pig heart and its application in preservation.Methods Five intact hearts from Guangxi Bama miniature pigs were selected as the experimental objects.Coronary artery casting specimens of the small pig hearts were made by perfusion and corrosion to explore the fabrication process of the small pig coronary artery casting model and three-dimensional(3D)model by using crystal-gutta percha embedding and 3D reconstruction technology.Results The result showed that,the model of small pig heart coronary artery cast embedding had high transparency,which could clearly observe the course and branch distribution of small pig heart coronary artery,and no cast branch was broken.The three-dimensional model constructs the anatomical structure of coronary artery in miniature pig heart,which has strong stereoscopic sense,no artifacts,and can be rotated and segmented at any angle in three-dimensional space.Conclusions The crystal embedded cast model can effectively protect the coronary artery cast specimens of miniature pigs,the 3D model can also provide a technical and empirical basis for 3D virtual simulation of animal models.

关 键 词：心冠状动脉铸型 三维重建 水晶包埋 铸型标本 小型猪 

分 类 号：R-33[医药卫生]