胎儿侧脑室前角间距与双顶径比值对完全性胼胝体缺失的诊断价值  

Diagnosis of Ratio of the Distance Between Anterior Horn of Bilateral Ventricles and the Biparietal Diameter of Fetal Inabsence of Corpus Callosum

作　　者：相光华[1] 黄苑铭[1] 缪华章[2] 何敬华[3] 徐玲[1] 邓雪红[1] 郑丽 XIANG Guanghua;HUANG Yuanming;MIAO Huazhang;HE Jinghua;XU Ling;DENG Xuehong;ZHENG Li(Department of UItrasonic Diagnosis,Guangdong Women and Children’s Hospital,Guangzhou 510010,China;不详)

机构地区：[1]广东省妇幼保健院超声诊断科,广东广州510010 [2]广东省妇幼保健院保健部,广东广州510010 [3]广东省妇幼保健院药学部,广东广州510010

出　　处：《中国医学影像学杂志》2021年第7期730-733,共4页Chinese Journal of Medical Imaging

摘　　要：目的探讨产前超声测量胎儿侧脑室前角间距与双顶径比值对完全性胼胝体缺失的诊断价值。资料与方法回顾性纳入53例妊娠20^(+3)~32^(+4)周确诊为完全性胼胝体缺失胎儿作为研究组,选择同期271例妊娠20~32^(+6)周正常单胎作为对照组,测量胎儿侧脑室前角间距与双顶径,比较两组胎儿侧脑室前角间距与双顶径的比值。结果研究组胎儿侧脑室前角间距、侧脑室前角间距与双顶径比值均显著大于对照组(F=581.162、731.615,P<0.001),不同孕周间胎儿侧脑室前角间距、侧脑室前角间距与双顶径比值差异有统计学意义(F=51.748、2.159,P<0.001)。研究组相同孕周胎儿侧脑室前角间距及侧脑室前角间距与双顶径比值均显著大于对照组(P<0.05)。随着孕周增加,两组胎儿侧脑室前角间距逐渐增宽。两组胎儿双顶径差异无统计学意义(F=0.468,P>0.05),不同孕周间两组胎儿双顶径差异有统计学意义(F=229.867,P<0.001)。研究组53例胎儿颅脑表现为透明隔腔消失,52例胎儿双侧侧脑室扩张呈泪滴样,14例胎儿第三脑室扩张并上抬,50例胎儿侧脑室前角间距与双顶径比值增大。结论胎儿侧脑室前角间距与双顶径比值可以作为产前超声筛查完全性胼胝体缺失的有效观察指标。Purpose To explore the diagnostic value of prenatal ultrasound measurement of the ratio of the distance between anterior horn of bilateral ventricles and the biparietal diameter of fetal in absence of corpus callosum.Materials and Methods Fifty-three pregnant women(20^(+3)-32^(+4) weeks)diagnosed as dysplasia of corpus callosum of fetal were retrospectively enrolled in the study group,and 271 normal singleton pregnancies(20-32^(+6) weeks)were included as the control group.The difference in the distance between anterior horn of bilateral ventricles and the biparietal diameter of fetal was analyzed.Results Compared with the control group,the distance between anterior horn of bilateral ventricles,the ratio of the distance between anterior horn of bilateral ventricles and the biparietal diameter in the study group were significantly higher(F=581.162 and 731.615,P<0.001).These two indicators was also significant difference in different gestational weeks between the two groups(F=51.748 and 2.159,P<0.001).As gestational week increased,the distance between anterior horn of bilateral ventricles gradually widened in both groups.there was no significant difference in the biparietal diameter between the two groups(F=0.468,P>0.05).The biparietal diameter with different gestational week was significant difference in two groups(F=229.867,P<0.001).In the case group,53 cases of fetal brain showed the absence of septum pelliculata,52 cases of bilateral lateral ventricle dilated with teardrop like,14 cases of fetal third ventricle dilated and lifted,50 cases of fetal lateral ventricle anterior angular spacing/double parietal diameter ratio increased.Conclusion The ratio of the distance between anterior horn of bilateral ventricles and the biparietal diameter of fetal is an effective observation index for the presence of fetal in dysplasia of corpus callosum by prenatal ultrasound screening.

关 键 词：先天畸形 完全性胼胝体缺失 超声检查 产前 间接征象 胎儿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R722.1[医药卫生—诊断学]