T4期胃癌患者腹腔热灌注化疗的临床护理路径选择  

The choices of clinical nursing path for patients with stage T4 gastric cancer after hyperthermic intraperitoneal chemotherapy

作　　者：杨婵萍[1] 李镠洋[1] 陈海珊 林淑辉[1] Yang Chanping

机构地区：[1]汕头大学医学院附属肿瘤医院,广东汕头515031

出　　处：《中医临床研究》2021年第14期122-125,共4页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨T4期胃癌患者腹腔热灌注化疗的临床护理路径选择的效果。方法:选取行腹腔热灌注化疗的T4期胃癌患者,共60例,采用随机数字表法进行随机分组,各30例,对照组施以常规护理,试验组施以临床护理路径选择模式,对患者的临床护理满意度、并发症情况及护理前后的生理功能、社会功能、躯体疼痛等生活质量评分、肝肾功能指标、血清肿瘤标志物癌胚抗原(Carcinoembryonic Antigen,CEA)、糖类抗原19-9(Carbohydrate Antigen 19-9,CA19-9)水平以及血清血管内皮生长因子(Vascular Endothelial Growth Factor,VEGF)、基质金属蛋白酶(Matrix Metalloprotinase,MMP)水平变化情况进行观察。结果:与护理前相比,护理后试验组的生理功能、社会功能、躯体疼痛等生活质量评分明显提升,肝肾功能指标明显改善,CEA、CA19-9、VEGF、MMP水平明显降低,试验组的临床护理满意度明显较高,并发症发生率明显较低,与对照组相比差异显著(P<0.05)。结论:T4期胃癌患者腹腔热灌注化疗的临床护理路径选择具有良好的效果,不仅能够提升患者的临床护理满意度与生活质量评分,改善肝肾功能指标,同时能够降低并发症发生率、CEA、CA19-9、VEGF、MMP水平。Objective:To explore the effects of the clinical nursing path selection on stage T4 gastric cancer patients with intraperitoneal hyperthermic chemotherapy.Methods:60 cases were selected and were divided into groups according to the random number table method,30 cases in each.The control group received routine care,and the experimental group adopted a clinical nursing path selection model.Results:Compared with before nursing,in the experimental group,the scores of life quality including physiological function,social function and physical pain after nursing were significantly improved,liver and kidney function indexes were significantly improved,and the levels of CEA,CA19-9,VEGF,and MMP were significantly reduced.Compared with the control group,the clinical nursing satisfaction in the experimental group was significantly higher,and the incidence of complications was significantly lower(P<0.05).Conclusion:The clinical nursing path selection for stage T4 gastric cancer patients with intraperitoneal hyperthermic chemotherapy shows good results.It can not only improve patients’clinical nursing satisfaction and quality of life scores,ameliorate liver and kidney function indicators,but also reduce the incidence of complications,CEA,CA19-9,VEGF,and MMP levels.

关 键 词：T4期胃癌 腹腔热灌注化疗 临床护理路径 

分 类 号：R735.2[医药卫生—肿瘤]