Nonalcoholic fatty pancreas disease:An emerging clinical challenge  

作　　者：Cheng-Lei Zhang Jing-Jiao Wang Jian-Ning Li Yi Yang 

机构地区：[1]Department of Clinical Laboratory,General Hospital of Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China [2]The Institute of Endocrinology,Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China [3]Department of Stomatology,General Hospital of Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China [4]School of Basic Medical Sciences,Ningxia Medical University,Yinchuan 750004,Ningxia Hui Autonomous Region,China

出　　处：《World Journal of Clinical Cases》2021年第23期6624-6638,共15页世界临床病例杂志

摘　　要：Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,but the pathogenesis is largely unknown.A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation,but NAFPD remains an under-recognized and non-independent disorder.Obesity,age,sex,race,and unhealthy lifestyle are established independent risk factors for NAFPD,which is strongly associated with metabolic syndrome,type 2 diabetes,pancreatitis,pancreatic fistula,pancreatic cancer,and nonalcoholic fatty liver disease.At present,imaging techniques are common diagnostic aids,but uniform criteria and consensus are lacking.Therapeutically,healthy diet,weight loss,and exercise are the mainstays to reduce pancreatic fat accumulation.It can be seen that there is a limited understanding of NAFPD at this stage and further exploration is needed.Previous studies have revealed that NAFPD may directly affect diagnosis and clinical decision-making.Therefore,exploring the pathophysiological mechanism and clinical associations of NAFPD is a major challenge for researchers and clinicians.

关 键 词：Nonalcoholic fatty pancreatic disease Pancreatic steatosis Obesity Metabolic syndrome Pancreatic disease PANCREAS 

分 类 号：R576[医药卫生—消化系统]