Health-related risky behaviors and their risk factors in adolescents with high-functioning autism  

作　　者：Ya-Jing Sun Ling-Zi Xu Zeng-Hui Ma Yu-Lu Yang Ting-Ni Yin Xiao-Yun Gong Zi-Lin Gao Yan-Ling Liu Jing Liu 

机构地区：[1]Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100191,China [2]Quanzhou Children’s and Women’s Hospital,Quanzhou 362000,Fujian Province,China [3]Department of Mathematics,Changzhi Medical College,Changzhi 046000,Shanxi Province,China

出　　处：《World Journal of Clinical Cases》2021年第22期6329-6342,共14页世界临床病例杂志

基　　金：Supported by National Key R&D Program of China,No.2017YFC1309900;Beijing Municipal Science&Technology Commission,No.Z171100001017088 and No.Z161100000116098.

摘　　要：BACKGROUND Health-related risky behaviors generally refer to behaviors that have a negative impact on health and quality of life.Health-related risky behaviors in adolescents with high-functioning autism(HFA)have not been well understood so far.Adolescents with HFA may have more health-related risky behaviors than neurotypical adolescents.AIM To investigate health-related risky behaviors and their risk factors with HFA.METHODS This is an observational study.Our study enrolled 110 adolescents aged 12-19-years-old meeting Diagnostic and Statistical Manual of Mental Disorders 4th edition criteria for HFA.They were recruited from Peking University Sixth Hospital.There were also 110 age,sex and nationality matched controls enrolled who came from a public school in Beijing,China.Both groups completed the Adolescents Health-related Risky Behavior Inventory.Nonparametric tests were carried out for comparison of the Adolescents Health-related Risky Behavior Inventory scores between the two groups.Expression recognition,the Inventory of Subjective Life Quality for Child and Adolescent,Chinese Wechsler Intelligence Scale for Children,Wechsler Intelligence Scale for Adult-Chinese Revised,Theory of Mind test and Autism Spectrum Screening Questionnaire were assessed in the autism group to explore factors associated with health-related risky behaviors.Multivariate regression analysis was conducted to explore the risk factors of health-related risky behaviors in the HFA group.RESULTS The results showed that the total score of the Adolescents Health-related Risky Behavior Inventory and scores of“aggression and violence,”“suicide and selfinjury,”“health compromising behavior”and“unprotected sex”subscales in the HFA group were significantly higher than those in the control group(Z range-4.197 to-2.213,P<0.05).Among the associated factors,poor emotional experience(B=-0.268,P<0.001),depression(B=-0.321,P<0.001),low score of intelligence(B=-0.032,P=0.042),low score of Theory of Mind test(B=-1.321,P=0.003)and poor adapt

关 键 词：High-functioning autism Adolescents Health-related risky behaviors Associated factors Risk factors Cross-sectional study 

分 类 号：R749.94[医药卫生—神经病学与精神病学]