水蛭粉的真空微波干燥工艺筛选  

Optimize the Vacuum Microwave Drying Process for Hirudo Powder

作　　者：潘丕阑 叶树兰 吴军军 PAN Pi-lang;YE Shu-lan;WU Jun-jun(Manufacturing laboratory of ho spital of Traditional Chin ese medicine in Ningde,Ningde 352000,China)

机构地区：[1]宁德市中医院制剂室,福建宁德352000

出　　处：《海峡药学》2021年第7期12-15,共4页Strait Pharmaceutical Journal

基　　金：福建中医药大学校管课题“医院中药制剂干燥工艺改良(课题编号:XB2019096)”。

摘　　要：目的筛选水蛭粉的最佳真空微波干燥工艺。方法采用五因素三水平的正交实验,以水蛭粉抗凝血酶活性单位和水分为量化考察指标,筛选水蛭粉的最佳干燥工艺。结果筛选的最佳真空微波干燥工艺为,干燥温度50℃,真空度0.9 MPa,干燥时间40 min,升温速度1℃/min,水蛭粉平辅厚度约2 cm(即每个烘盘装水蛭粉约1 kg)。结论筛选的最佳干燥工艺适用于水蛭粉的真空微波干燥工序。OBJECTIVE To optimize the best vacuum microwave drying process for Hirudo powder.METHODS Optimize the best drying process accord ing to antithrombin activity unit and water contain of Hirudo powder,adopt by o rthogonal experiment with five factors and three levels.RESULTS The best vacuum microwave drying process stand for the drying temperature was 50℃,the vacuum degree was 0.9 MPa,the drying time was 40 min,the rate of te mp erature was 1℃per min and the thickness of Hirudo powder was 2 cm nearly each plate(about 1 kg load per plate).CONCLUSION The best vacuum mi crowave drying process had optimized suit for drying of Hirudo powder.

关 键 词：水蛭粉 真空微波干燥 工艺筛选 

分 类 号：R94[医药卫生—药剂学]