1990年与2017年中国8种消化道疾病的疾病负担分析  

Analysis of the burden of gastrointestinal diseases between 1990 and 2017 in China

作　　者：李路遥 郑忠立 甘信利 郭幸沛 訾豪 菅志远 任学群[1] 曾宪涛 Lu-Yao LI;Zhong-Li ZHENG;Xin-Li GAN;Xing-Pei GUO;Hao ZI;Zhi-Yuan JIAN;Xue-Qun REN;Xian-Tao ZENG(Institutes of Evidence-Based Medicine and Knowledge Translation,Henan University,Kaifeng 475000,Henan Province,China;Center for Evidence-Based and Translational Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Department of General Surgery,Sanmenxia Central Hospital,Affiliated to Henan University of Science and Technology,Sanmenxia 472000,Henan Province,China;Department of Gastrointestinal Surgery,Affiliated Hospital of Guilin Medical University,Guilin 541000,Guangxi Province,China)

机构地区：[1]河南大学循证医学与临床转化研究院,河南开封475000 [2]武汉大学中南医院循证与转化医学中心,武汉430071 [3]河南科技大学附属三门峡市中心医院普通外科,河南三门峡472000 [4]桂林医学院附属医院胃肠外科,广西桂林541001

出　　处：《医学新知》2021年第4期249-256,共8页New Medicine

基　　金：国家发改委、国家卫健委疑难病症诊治能力提升工程项目(发改办社会[2018]347号)。

摘　　要：目的对比分析1990年与2017年中国8种消化道疾病的疾病负担。方法采用2017年全球疾病负担数据,分析我国消化道疾病的发病率、死亡率、伤残调整寿命年、早死损失寿命年、伤残损失寿命年等指标及其变化趋势,分析不同性别和年龄人群的消化道疾病负担特点。结果1990年至2017年,8种消化道疾病的发病例数均增加。2017年标化伤残调整寿命年率排名前3的疾病均为消化道恶性肿瘤,分别为胃癌(391.66/10万)、食管癌(222.58/10万)和结直肠癌(216.19/10万)。在标化死亡率方面,仅有结直肠癌标化死亡率升高8.20%,增长至10.10/10万,其余均降低。随着年龄的增长,疾病负担逐渐增加。与女性相比,男性消化道疾病发病率低,但死亡率和伤残调整寿命年率均较高。结论消化道恶性肿瘤导致的疾病负担占据我国消化道疾病负担的主要地位,男性高于女性,结直肠癌等恶性肿瘤的防治是消化道疾病防控的重点。Objective To compare and analyze the disease burden of gastrointestinal diseases in China between 1990 and 2017.Methods The Global Burden of Disease Study 2017 was searched for the following indicators:morbidity,mortality,disability adjusted life years(DALY),year of life lost(YLL),and years lived with disability(YLD)which were then analyzed.The gastrointestinal disease burden characteristics of people of different genders and ages were explored.Results Between 1990 and 2017,the incidence of 8 gastrointestinal diseases increased.The top three standardized DALY were malignant gastrointestinal tumors:comprising gastric cancer(391.66 per 100,000),esophageal cancer(222.58 per 100,000)and colorectal cancer(216.19 per 100,000).The only increase in standardized mortality was for colorectal cancer which increased by 8.20%,from 9.33 per 100,000 to 10.10 per 100,000.The burden of disease increases with age.Compared with females,males have lower incidence of gastrointestinal diseases,but mortality and DALY rates are higher.Conclusion The burden of disease caused by malignant gastrointestinal tumors accounts for the main burden of gastrointestinal diseases in China,and men are higher than women.Malignant tumors such as colorectal cancer are the focus of prevention and control measures for gastrointestinal diseases.

关 键 词：消化道疾病 胃癌 食管癌 结直肠癌 胃炎 十二指肠炎 阑尾炎 消化性溃疡病 炎症性肠病 肠梗阻 疾病负担 

分 类 号：R57[医药卫生—消化系统]