乳腺癌患者的围手术期抑郁、焦虑症状与癌症复发恐惧感的关系  

Relationships between perioperative depression,anxiety symptoms and fear of cancer recurrence in breast cancer patients

作　　者：朱松颖[1] 白华羽 高蔚[1] 孔晓丽[1] 高蕾[2] Zhu Songying;Bai Huayu;Gao Wei;Kong Xiaoli;Gao Lei(Department of Breast Surgery,Qilu Hospital of Shandong University,Jinan 250012,China;Operating Theatre of Qilu Hospital of Shandong University,Jinan 250012,China)

机构地区：[1]山东大学齐鲁医院乳腺外科,济南250012 [2]山东大学齐鲁医院手术室,济南250012

出　　处：《中国实用护理杂志》2021年第23期1806-1810,共5页Chinese Journal of Practical Nursing

摘　　要：目的分析乳腺癌患者围手术期抑郁、焦虑症状对癌症复发恐惧感的预测作用。方法2019年5月至2020年5月在山东大学齐鲁医院选取194例围手术期乳腺癌患者纳入研究。采用一般资料调查表、广泛性焦虑量表(GAD-7)、患者健康问卷(PHQ-9)和恐惧疾病进展简化量表(FOR-Q-SF)分别在入院时和术后2周对患者的抑郁、焦虑症状和癌症复发恐惧感进行调查。结果乳腺癌患者围手术期焦虑、抑郁症状均为癌症复发恐惧感的显著预测因素(B值为2.325,OR值为10.22,P<0.05;B值为2.570,OR值为13.07,P<0.05),且术后存在抑郁、焦虑症状的患者产生癌症复发恐惧感的风险更高(OR值为7.653~25.403,P<0.01)。结论对于存在负性情绪和恐惧疾病进展的乳腺癌患者要帮助其提高心理应对能力,鼓励患者积极配合后续治疗,改善预后,提高整体生命质量。Objective To investigate the predictive effect of perioperative depression and anxiety symptoms in breast cancer patients on the fear of cancer recurrence.Methods A total of 194 patients with breast cancer during perioperative period from May 2019 to May 2020 in Qilu Hospital of Shandong University were selected.The depression,anxiety and fear of cancer recurrence were investigated by the general information questionnaire,the Generalized Anxiety Disorder-7(GAD-7),the Patient Health Questionnaire-9(PHQ-9)and the Fear of Progression Questionnaire-Short Form(FOR-Q-SF)at admission and two weeks after surgery,respectively.Results Perioperative depression and anxiety symptoms of breast cancer patients were significant predictors of fear of cancer recurrence(B value was 2.325,OR value was 10.22,P<0.05;B value was 2.570,OR value was 13.07,P<0.05),and patients with depression and anxiety symptoms after surgery were at higher risk of fear of cancer recurrence(OR values were 7.653-25.403,P<0.01).Conclusions For breast cancer patients with negative emotions and fear of disease progression,it is necessary to help them improve their psychological coping ability,encouraging patients to actively cooperate with follow-up treatment,improving the prognosis,and improving their overall quality of life.

关 键 词：乳腺肿瘤 癌症复发恐惧 抑郁 焦虑 

分 类 号：R73[医药卫生—肿瘤]