CIDP的诊断及治疗进展  

Progresses in diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy

作　　者：牛婧雯 管宇宙 刘明生 崔丽英 Niu Jingwen;Guan Yuzhou;Liu Mingsheng;Cui Liying(Department of Neurology,Peking Union Medical College Hospital)

机构地区：[1]中国医学科学院北京协和医院神经科,北京100000

出　　处：《重庆医科大学学报》2021年第7期750-753,共4页Journal of Chongqing Medical University

摘　　要：慢性炎性脱髓鞘性神经根周围神经病(chronic inflammatory demyelinating polyradiculoneuropathy,CIDP)是最常见的慢性免疫介导的周围神经病。早期准确的诊断对于及时治疗及预防不可逆的神经病变具有重要价值。本文从临床类型、诊断进展、治疗现状几个方面对CIDP近年来的进展进行归纳总结。诊断进展方面,主要包括特异性抗神经节及节旁蛋白Ig G4抗体的发现,神经超声和神经磁共振所示周围神经及神经根的增粗,可作为诊断的有效补充手段。Chronic inflammatory demyelinating polyradiculoneuropathy(CIDP)is the most common chronic immune-mediated peripheral neuropathy.Early and accurate diagnosis is crucial for treatment and prevention of irreversible nerve damage.This article reviews recent progresses in clinical types,diagnosis and treatment of CIDP.The discovery of specific IgG4 antibodies against nodal and paranodal proteins,as well as nerve/nerve root enlargement revealed by nerve ultrasound and MRI,could be effective supplemental tools for diagnosis.

关 键 词：慢性炎性脱髓鞘性神经根周围神经病 诊断 治疗 

分 类 号：R745[医药卫生—神经病学与精神病学]