颌面部原发性皮肤间变大细胞淋巴瘤1例报告及文献复习  

Primary facial CD30^(+) positive anaplastic large cell lymphoma:report of one case and review of the literature

作　　者：杨彩秀 卜令学[1] 陈立强[1] 范存晖[1] 王双义[1] YANG Cai-xiu;BU Ling-xue;CHEN Li-qiang;FAN Cun-hui;WANG Shuang-yi(Stonidlology Center of Affiliated Hospital of Qingdao University,School of Stomatology of Qingdao University,Qingdao Stomatologicul Digital Medicine and 3D Printing Engineering Laboratory,Qingdao 266003,Shandong Province,China)

机构地区：[1]青岛大学附属医院口腔医学中心,青岛大学口腔医学院,青岛市口腔数字医学与3D打印工程实验室,山东青岛266003

出　　处：《中国口腔颌面外科杂志》2021年第4期380-384,共5页China Journal of Oral and Maxillofacial Surgery

摘　　要：原发性CD30^(+)间变性大细胞淋巴瘤是一种少见的非霍奇金淋巴瘤,该病主要好发于60岁左右,常发生于四肢和躯干,临床检查为质韧、边界清楚、结节状肿物。组织病理学检查显示皮下组织内有大量淋巴细胞,形态学结合免疫组织化学是诊断本病较为有效的方法。皮肤原发性病变临床少见,原发于颌面部者更为罕见。本文对临床上发现的1例原发于颌面部皮肤的间变大细胞淋巴瘤做一报告,并对相关文献进行复习。Primary CD30^(+) positive anaplastic large cell lymphoma is a rare non-Hodgkin’s lymphoma.The disease mainly occurs around 60 years old,often in the limbs and trunk.Clinical examination often found tough,well demarcated nodular mass.Histopathological examination showed that a large number of lymphocytes are in the subcutaneous tissue.Morphology combined with immunohistochemical is more effective for diagnosis of this disease.Primary cutaneous ALCL is relatively rare,and primary anaplastic cell lymphoma occuring in the maxillofacial skin is much rare in clinic.In order to improve the diagnosis and treatment of the disease by oral and maxillofacial surgeons,this paper reported a case of ALCL in the maxillofacial skin and review the relevant literatures.

关 键 词：淋巴瘤 CD30^(+)间变 免疫组织化学 

分 类 号：R739.8[医药卫生—肿瘤]