胸腔镜下肺癌根治术治疗早期非小细胞肺癌的效果及安全性分析  

Analysis of the effect and safety of thoracoscopic radical resection of lung cancer in the treatment of early-stage non-small cell lung cancer

作　　者：付武君 FU Wu-jun(Hepatobiliary/Cardiothoracic Surgery Department,Zhongxian People’s Hospital,Chongqing 404300,China)

机构地区：[1]重庆市忠县人民医院肝胆/心胸外科,404300

出　　处：《中国实用医药》2021年第24期9-11,共3页China Practical Medicine

摘　　要：目的评价早期非小细胞肺癌者行胸腔镜肺癌根治术的价值。方法92例早期非小细胞肺癌者,根据治疗方法不同分为微创组和开胸组,每组46例。微创组采用胸腔镜下肺癌根治术,开胸组采用开胸肺癌根治术。比较两组患者手术前后肺功能指标(肺活量、最大通气量、第一秒用力呼气量)、围术期指标(手术时间、引流时间、淋巴结清扫数、住院时间、引流量、疼痛感)、术后并发症发生情况(肺部感染、肺栓塞、出血)。结果术后,微创组患者肺活量(2.60±0.14)L、最大通气量(72.05±2.13)L/min、第一秒用力呼气量(1.92±0.11)L均高于开胸组的(2.34±0.16)L、(66.83±2.38)L/min、(1.76±0.15)L,差异均具有统计学意义(P<0.05)。微创组患者手术时间(149.72±20.72)min、引流时间(4.01±0.66)d、住院时间(11.49±1.07)d均短于开胸组的(172.91±20.66)min、(5.52±1.19)d、(14.82±2.13)d,淋巴结清扫数(12.37±1.14)个多于开胸组的(10.44±1.06)个、引流量(1033.41±145.94)ml和疼痛感(1.04±0.33)分均低于开胸组的(1364.78±144.82)ml、(2.18±0.47)分,差异均具有统计学意义(P<0.05)。微创组术后并发症发生率10.87%低于开胸组的45.65%,差异具有统计学意义(P<0.05)。结论胸腔镜肺癌根治术安全性高,除减少早期非小细胞肺癌者术后并发症外,还能使其术后恢复时间缩短,且早期非小细胞肺癌者肺功能可得到改善,建议推广。Objective To evaluate the value of thoracoscopic radical resection of lung cancer in the treatment of early-stage non-small cell lung cancer.Methods A total of 92 patients with early-stage non-small cell lung cancer were divided into minimally invasive group and thoracotomy group,with 46 cases in each group.The minimally invasive group was treated with thoracoscopic radical resection of lung cancer,and the thoracotomy group was treated with radical thoracotomy for lung cancer.The pulmonary function indexes(vital capacity,maximum ventilation,forced expiratory volume in the first second),perioperative indexes(operation time,drainage time,number of lymph node dissection,hospitalization time,drainage volume,pain feeling)and occurrence of postoperative complications(pulmonary infection,pulmonary embolism and bleeding)were compared between the two groups.Results After surgery,the vital capacity(2.60±0.14)L,maximum ventilation(72.05±2.13)L/min,and forced expiratory volume in the first second(1.92±0.11)L of the minimally invasive group were higher than(2.34±0.16)L,(66.83±2.38)L/min,(1.76±0.15)L of the thoracotomy group,and the differences were statistically significant(P<0.05).The operation time(149.72±20.72)min,drainage time(4.01±0.66)d and hospitalization time(11.49±1.07)d of the minimally invasive group were shorter than(172.91±20.66)min,(5.52±1.19)d and(14.82±2.13)d of the thoracotomy group,the number of lymph node dissection(12.37±1.14)nodes was more than(10.44±1.06)nodes of the thoracotomy group,and the drainage volume(1033.41±145.94)ml and pain feeling(1.04±0.33)points were lower than(1364.78±144.82)ml and(2.18±0.47)points of the thoracotomy group.All the difference was statistically significant(P<0.05).The incidence of postoperative complications of the minimally invasive group was 10.87%,which was lower than 45.65%of the thoracotomy group,and the difference was statistically significant(P<0.05).Conclusion Thoracoscopic radical resection of lung cancer is safe.In addition to reducing postoperati

关 键 词：开胸肺癌根治术 早期非小细胞肺癌 安全性 临床疗效 胸腔镜 

分 类 号：R734.2[医药卫生—肿瘤]