Estrogen Biosynthesis and Its Regulation in Endometriosis  

作　　者：Qiu-Ming Qi Sun-Wei Guo Xi-Shi Liu 

机构地区：[1]Department of Gynecology,Shanghai Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China [2]Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases,Fudan University,Shanghai 200011,China

出　　处：《Reproductive and Developmental Medicine》2017年第1期55-61,共7页生殖与发育医学（英文版）

基　　金：supported in part by grants 81471434(SWG),81530040(SWG),81370695(XSL),and 81671436(XSL);the National Natural Science Foundation of China.

摘　　要：Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis.It affects approximately 10%women of reproductive age.Although its etiology and pathogenesis remain poorly understood,it is characterized by the elevated local production of estrogen in the endometriotic tissues.In this paper,we review the mechanisms of estrogen biosynthesis and its regulation in endometriosis.

关 键 词：17 beta-Hydroxysteroid Dehydrogenase Type 2 AROMATASE ENDOMETRIOSIS Estrogen Biosynthesis Steroidogenic Acute Regulatory Protein 

分 类 号：R711.71[医药卫生—妇产科学]