AROMATASE

作品数：31被引量：104H指数：5
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相关作者：代解杰张浩吴德生詹立孙海波更多>>
相关机构：四川大学华东师范大学上海交通大学中国医学科学院中国协和医科大学更多>>
相关期刊：《Journal of Ocean University of China》《Science China(Life Sciences)》《Reproductive and Developmental Medicine》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金湖北省自然科学基金高等学校学科创新引智计划更多>>
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Toxic effects of monocrotophos and glyphosate on the female reproductive organ and aromatase gene expression in climbing perch
《Aquaculture and Fisheries》2025年第1期79-88,共10页Sujata Mohapatra Rajesh Kumar Jitendra Kumar Sundaray Lakshman Sahoo Mohd Ashraf Rather Sangita Dixit Vasam Manohar Kiran Rasal Sukanta K.Pradhan 
financial support from Department of Biotechnology,Govt of India(BT/PR28560/AAQ/3/919/2018).
Monocrotophos(MCP)and Glyphosate(GLY)are used as an insecticide and herbicide respectively in agricultural fields in India and other developed countries.Since agricultural fields are located close to water bodies,ther...
关键词：AROMATASE OVARY Histology Molecular docking Anabas testudineus 
Lactobacillus gasseri CCFM1255 promotes peripheral estrogen synthesis in ovariectomized rats by modulating the gut microbiome and serum metabolome
《Food Science and Human Wellness》2024年第6期3301-3310,共10页Qian Chen Haiqin Chen Jianxin Zhao Wei Chen Gang Wang 
funded by the National Natural Science Foundation of China(32021005);the Fundamental Research Funds for the Central Universities(JUSRP622020,JUSRP51501);the Program of Collaborative Innovation Centre of Food Safety and Quality Control in Jiangsu Province.
The decline in ovarian estrogen production is known to have detrimental health consequences and negatively affect the quality of life in menopausal women.Increasing estradiol levels is key to preventing disease in men...
关键词：ESTRADIOL AROMATASE Gut microbiota Amino acids 
Molecular Docking Studies of Estrone-Coumarin Derivatives as Aromatase and 17β-HSD1 Inhibitors Related to Hormone Receptor Positive (HR+) Breast Cancer
《Advances in Enzyme Research》2022年第4期83-100,共18页Silvia Alejandra Meza-Ireta Blanca Colin-Lozano Penélope Merino-Montiel José Luis Vega-Báez Sara Montiel-Smith 
Hormone Receptor positive (HR+) breast cancer is the most common malignancy in women. New strategies in the treatments have targeted the estrogen biosynthesis pathways including the inhibition of the aromatase and 17...
关键词：ESTRONE COUMARINS Aromatase Inhibitors 17β-HSD1 Inhibitors Molecular Docking 
Obesity as potential breast cancer risk factor for postmenopausal women被引量：5
《Genes & Diseases》2021年第2期117-123,共7页Swati Sucharita Mohanty Prafulla Kumar Mohanty 
Breast cancer is the second highest prevalent cancer globally after lung cancer with 2.09 million cases during 2018.Adults about 1.9 billion were overweight and over 650 million out of these were obese during 2016.The...
关键词：ADIPOCYTE AROMATASE Breast cancer ESTROGEN OBESITY 
RES transformation for biosynthesis and detoxification
《Science China(Life Sciences)》2020年第9期1297-1302,共6页Jin-Quan Huang Jia-Ling Lin Xiao-Xiang Guo Xiu Tian Ye Tian Xiao-Xia Shangguan Ling-Jian Wang Xin Fang Xiao-Ya Chen 
the financial support from the National Natural Science Foundation of China(31690092,31788103 to X.Chen and 31872666 to X.Fang);the Ministry of Agriculture of China(2016ZX08010002-005 to X.Shangguan);the Chinese Academy of Sciences(QYZDY-SSW-SMC026 and 153D31KYSB20160074 to X.Chen);the Young Elite Scientists Sponsorship Program by CAST(2019QNRC001)。
The reactive electrophilic species(RES), typically the molecules bearing α,β-unsaturated carbonyl group, are widespread in living organisms and notoriously known for their damaging effects. Many of the mycotoxins re...
关键词：reactive electrophilic species GLYOXALASE GOSSYPOL MYCOTOXIN DETOXIFICATION AROMATASE 
Neoadjuvant endocrine therapy: A potential strategy for ER-positive breast cancer被引量：5
《World Journal of Clinical Cases》2019年第15期1937-1953,共17页Li-Tong Yao Mo-Zhi Wang Meng-Shen Wang Xue-Ting Yu Jing-Yi Guo Tie Sun Xin-Yan Li Ying-Ying Xu 
Supported by the National Natural Science Foundation of China,No.81773083
A potential strategy for patients with estrogen receptor(ER)-positive breast cancer is necessary to replace neoadjuvant chemotherapy which has limited benefit.Neoadjuvant endocrine therapy(NAE)has been indicated to be...
关键词：Breast cancer NEOADJUVANT ENDOCRINE therapy NEOADJUVANT chemotherapy AROMATASE inhibitor Palbociclib KI67 GENOMIC ASSAY 
Effect of Jianpi Bushen formula on aromatase-inhibitor-associated bone loss after menopause被引量：2
《Journal of Traditional Chinese Medicine》2018年第6期879-889,共11页Dai Yan Chen Qingqing Guan Ruodan Xu Rui Qiu Chang Song Xue Guo Qianqian Wang Zhiyu Chen Qianjun 
Supported by a TCM Scientific and Technological Research Fund of Guangdong Provincial Hospital of Chinese Medicine,People's Republic of China(No.2011KT371)
OBJECTIVE: To investigate the effect of Jianpi Bushen(JPBS) formula on aromatase inhibitor(AI)-associated bone loss after menopause.METHODS: Six-month-old female rats were randomly divided into 6 groups: a sham group,...
关键词：AROMATASE INHIBITORS MENOPAUSE Bone RESORPTION OSTEOGENESIS Jianpi Bushen FORMULA 
Estrogen and oxytocin involvement in social preference in male mice:a study using a novel long-term social preference paradigm with aromatase,estrogen receptor-αand estrogen receptor-β,oxytocin,and oxytocin receptor knockout male mice
《Integrative Zoology》2018年第6期698-710,共13页Mumeko C.TSUDA Kazuyo NAGATA Shoko SAGOSHI Sonoko OGAWA 
This work was supported by Grants-in-Aid for Scientific Research(23240057 and 15H05724);the University of Tsukuba Research Project(to S.O.).
Certain aspects of social behavior help animals make adaptive decisions during encounters with other animals.When mice choose to approach another conspecific,the motivation and preference behind the interaction is not...
关键词：AROMATASE estrogen receptor oxytocin receptor social motivation social preference 
Estrogen Biosynthesis and Its Regulation in Endometriosis
《Reproductive and Developmental Medicine》2017年第1期55-61,共7页Qiu-Ming Qi Sun-Wei Guo Xi-Shi Liu 
supported in part by grants 81471434(SWG),81530040(SWG),81370695(XSL),and 81671436(XSL);the National Natural Science Foundation of China.
Endometriosis is a common benign gynecological disorder with an enigmatic etiology and pathogenesis.It affects approximately 10%women of reproductive age.Although its etiology and pathogenesis remain poorly understood...
关键词：17 beta-Hydroxysteroid Dehydrogenase Type 2 AROMATASE ENDOMETRIOSIS Estrogen Biosynthesis Steroidogenic Acute Regulatory Protein 
Experimental Sex Inversion of Chicken Embryos at Aromatase Inhibition, Estrogen Receptor Modulation, DNA Demethylation and Progesterone Treatment
《Natural Science》2016年第11期451-459,共9页Antonina V. Trukhina Natalia A. Lukina Aleksandr F. Smirnov 
The work was carried out by microinjections of an aromatase inhibitor letrozole, an estrogen receptor modulator tamoxifen in incubated eggs Gallus g. domesticus, the first day of incubation. It also used 5-azacytidine...
关键词：Gallus gallus Sex Determination AROMATASE GONAD DMRT1 
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