Hormone Receptor positive (HR+) breast cancer is the most common malignancy in women. New strategies in the treatments have targeted the estrogen biosynthesis pathways including the inhibition of the aromatase and 17...
support provided by the Natural Sciences and Engineering Research Council of Canada (NSERC) under the project Reducing Environmental Pollution from Veterinary Antibiotics, Endocrine Disruptive Chemicals, and Pathogens in Livestock Manure;the Department of Bioresource Engineering, McGill University for providing a Liliane and David Stewart Fellowship in Water Resources for support of this research work
Most animals, including humans, produce natural sex hormones such as estrogens: 17β-estradiol(E2) and estrone(E1). These compounds are able to disrupt the reproductive systems of living organisms at trace concentrati...
Three series of novel steroidal thiazole derivatives were synthesized by microwave assisted one-potreaction from pregnenolone, testosterone and estrone, respectively. Their structures were characterized by IR, NMRand ...
Supported by Fund of Harbin Provincial Education Department(2014AB3BN041)
A method was developed for the simultaneous determination of four kinds of estrogens (hexoestrol, diethylstilbestrol, estrone, and 17-beta-estradiol) in feed by gas chromatography-mass spectrometry (GC-MS). After ...
supported by a POSDRU grant;No.159/1.5/S/136893 grant with title:‘Parteneriat strategic pentru crecterea calitarii cercetarii stiintifice din universitatile medicale prin acordarea de burse doctorale?i postdoctorale-Doc Med.Net_2.0’
Genistein, the main isoflavone from soy, and bisphenol A (BPA), a food contaminant, are considered ubiquitous xenoestrogens. Here we investigated the influence of genistein and BPA on estrone (El) metabolism in ra...
Hydrophobic acid organic matter (HpoA) extracted from treated effluent has been known to improve the rejection of steroid hormone estrone by reverse osmosis (RO) and nanofiltration (NF) membranes. In this study,...
supported by Natural Science Foundation of China(U1301214);Guangdong Natural Science Foundation(S2013030013338);the PhD Programs Foundation of Ministry of Education of China(20114404130002);National Department Public Benefit Research Foundation(201003008-08)
Estrone has been identified as a potential endocrine-disrupting chemical (EDC)[1]. Estrone is usually quantified by gas chromatography-mass spectrometry (GC-MS), GC-MS/MS, high performance liquid chromatography (...
supported by the National Natural Science Foundation of China (51079049);Qing Lan Project of Jiangsu Province
Objective To assess the single and combined effects of estrone (El) and 1713-estradiol (E2) on goldfish ( Carassius auratus). Methods Batch tests were conducted. Serum levels of vitellogenin (VTG) and E2, gona...
supported by the Ministry of Education of China under the scheme of Key Project of Innovation (Grant No. 705013);the National Natural Science Foundation of China under the Scheme of National Creative Research Groups (Grant No. 50821002)
Permanganate was used as an oxidant to control estrone in the present study. Kinetics was determined at pH 2.5-9.4 and temperature 15–40°C for the reaction of estrone with potassium permanganate. It was found that t...
supported by the grant from Sasaki Environment Technology Foundation to T.Tanaka
Natural and synthetic estrogens from sewage treatment systems are suspected to influence the reproductive health of the animals in the rivers. In this article, we investigated the enzymatic treatment of three estroge...