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Supplementation of serine in low-gossypol cottonseed meal-based diet improved egg white gelling and rheological properties by regulating ovomucin synthesis and magnum physiological function in laying hens: 《Journal of Integrative Agriculture》2025年第3期1152-1166,共15页Jianmin Zhou Yu Fu Uchechukwu Edna Obianwuna Jing Wang Haijun Zhang Xiubo Li Guanghai Qi Shugeng Wu; financially supported by the National Natural Science Foundation of China(32072774);the China Postdoctoral Science Foundation(2023M733822);the Beijing Innovation Consortium of Agriculture Research System(BAIC04),China;the earmarked fund for CARS National System for Layer Production Technology,China(CARS-40);the Agricultural Science and Technology Innovation Program(ASTIP)of the Chinese Academy of Agricultural Sciences。; This study examined the effect of dietary serine(Ser)on egg white quality,ovomucin content of laying hens fed low-gossypol cottonseed meal(LCSM)-based diet and sought to explore the regulatory mechanism underlying the...; 关键词：egg white quality low-gossypol cottonseed meal laying hen OVOMUCIN SERINE

Gossypol is the main limiting factor in the application of cottonseed meal in grass carp feed production:Involvement of growth,intestinal physical and immune barrier,and intestinal microbiota: 《Water Biology and Security》2024年第4期77-90,共14页Yong Shi Lei Zhong Yuanxiang Liu Shuang Zheng Shude Xu Shouqi Xie Yi Hu; The objective of this study is to investigate the effects of free gossypol in cottonseed meal(CM)on the growth and intestinal health of grass carp,as well as to determine whether free gossypol is the primary factor re...; 关键词：Antinutritional factors Growth performance Intestinal health Microbiomics Plant protein

Mirids secrete a TOPLESS targeting protein to enhance JA-mediated defense and gossypol accumulation for antagonizing cotton bollworms on cotton plants: 《Molecular Plant》2024年第11期1687-1701,共15页Yu-Pei Mu Dian-Yang Chen Yu-Jie Liu Ming-Yu Zhu Xian Zhang Yin Tang Jia-Ling Lin Mu-Yang Wang Xiao-Xia Shangguan Xiao-Ya Chen Chengshu Wang Ying-Bo Mao; supported by Biological Breeding-Major Projects(2023ZD04070);the National Natural Science Foundation of China(32072430 and 32000221);the Science and Technology Commission of Shanghai Municipality(22ZR1469300 and 21ZR1471000).; Most coexisting insect species exhibit stunted growth compared to individual species on plants.This phenomenon reflects an interspecific antagonism drawing extensive attention,while the underlying mechanisms remain la...; 关键词：oral secretion plant defense co-repressor TOPLESS MIRIDS Apolygus lucorum cotton bollworms Helicoverpa armigera

Probiotic Pediococcus pentosaceus restored gossypol-induced intestinal barrier injury by increasing propionate content in Nile tilapia: 《Journal of Animal Science and Biotechnology》2024年第4期1688-1703,共16页Feifei Ding Nannan Zhou Yuan Luo Tong Wang Weijie Li Fang Qiao Zhenyu Du Meiling Zhang; supported by the Provincial Science and Technology Innovative Program for Carbon Peak and Carbon neutrality of Jiangsu of China (BE2022422);National Natural Science Foundation of China (32373145)。; Background Intestinal barrier is a dynamic interface between the body and the ingested food components, however, dietary components or xenobiotics could compromise intestinal integrity, causing health risks to the hos...; 关键词：Gut barrier injury GOSSYPOL ISCs proliferation Nlrc3 PROPIONATE

A comprehensive overview of cotton genomics,biotechnology and molecular biological studies被引量：13: 《Science China(Life Sciences)》2023年第10期2214-2256,共43页Xingpeng Wen Zhiwen Chen Zuoren Yang Maojun Wang Shuangxia Jin Guangda Wang Li Zhang Lingjian Wang Jianying Li Sumbul Saeed Shoupu He Zhi Wang Kun Wang Zhaosheng Kong Fuguang Li Xianlong Zhang Xiaoya Chen Yuxian Zhu; the National Natural Science Foundation of China(32200286);the China Postdoctoral Science Foundation(2022TQ0240,2022M722470)。; Cotton is an irreplaceable economic crop currently domesticated in the human world for its extremely elongated fiber cells specialized in seed epidermis,which makes it of high research and application value.To date,nu...; 关键词：COTTON genome assembly genome editing fiber development GOSSYPOL plant architecture oil utilization genetic breeding

Ponatinib and gossypol act in synergy to suppress colorectal cancer cells by modulating apoptosis/autophagy crosstalk and inhibiting the FGF19/FGFR4 axis被引量：1: 《Asian Pacific Journal of Tropical Biomedicine》2023年第3期131-138,共8页Naglaa M.El-Lakkany Hadeel H.Elkattan Alaa E.Elsisi; financial support from the Theodor Bilharz Research Institute;Warrak El-Hadar;Imbaba;Giza 12411,Egypt。; Objective:To evaluate the efficacy of ponatinib plus gossypol against colorectal cancer HCT-116 and Caco-2 cells.Methods:Cells were treated with ponatinib and/or gossypol at increasing concentrations to evaluate syner...; 关键词：AUTOPHAGY APOPTOSIS Cell viability FGF19/FGFR4 GOSSYPOL PONATINIB HCT-116 CACO-2 Colorectal cancer

A reference-grade genome assembly for Gossypium bickii and insights into its genome evolution and formation of pigment glands and gossypol被引量：1: 《Plant Communications》2023年第1期13-27,共15页Kuang Sheng Yue Sun Meng Liu Yuefen Cao Yifei Han Cheng Li Uzair Muhammad Muhammad Khan Daud Wanru Wang Huazu Li Samrana Samrana Yixuan Hui Shuijin Zhu Jinhong Chen Tianlun Zhao; supported by the National Key Technology R&D Program of China(2016YFD0101404);the Chinese Agricultural Research System(CARS-18-25);the Jiangsu Collaborative Innovation Center for Modern Crop Production.; The pigment gland is a morphological characteristic of Gossypium and its related genera.Gossypium bickii(G_(1))is characterized by delayed pigment gland morphogenesis in the cotyledons.In this study,a referencegrade g...; 关键词：Gossypium bickii GENOME evolution GOSSYPOL pigment glands

New function of gossypol,a natural product of cotton被引量：2: 《Journal of Cotton Research》2022年第4期42-43,共2页HUANG Jinquan CHEN Xiaoya; This research was supported by grants from the National Natural Science Foundation of China(31788103);the Chinese Academy of Sciences(XDB27020207).; Cotton plants are not only the global crops integrating fiber,oil and protein(Hu et al.2020;Xiao et al.2017),but also the medicinal plants with potent application values,which were well described in the most complete ...; 关键词：removing integrating CROPS

Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol被引量：1: 《Acta Biochimica et Biophysica Sinica》2022年第1期64-76,共13页Meiyan Zhong Yuanting Huang Bo Zeng Lihui Xu Chunsu Zhong Jiahao Qiu Xunjia Ye Mingye Chen Bo Hu Dongyun Ouyang Xianhui He; This work was supported by the grants from the National Natural Science Foundation of China(No.81773965 to X.H.and No.81873064 to D.O.).; Macrophages are critical sentinel cells armed with multiple regulated necrosis pathways,including pyroptosis,apoptosis followed by secondary necrosis,and necroptosis,and are poised to undergo distinct form(s)of necros...; 关键词：BH3-mimetic GOSSYPOL macrophages PYROPTOSIS secondary necrosis NECROPTOSIS

An in vitro and in silico study of anti-dermatophytic activity of gossypol from fruits of Thespesia populnea(L.)Sol.ex Correa: 《Asian Pacific Journal of Tropical Biomedicine》2021年第12期543-552,共10页Anuthara R Sebastian Jose Midhun Jyothis Mathew; Objective:To isolate,purify,and characterize gossypol from the fruits of Thespesia populnea(L)Sol.ex Correa,test its antidermatophytic activity,identify its targets on the dermatophyte,and confirm the binding of gossy...; 关键词：Thespesia populnea GOSSYPOL Anti-dermatophytic activity Trichophyton mentagrophytes Mechanism of action Gene expression Molecular docking METALLOPROTEASE MEP4 Isocitrate lyase ICL

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