METALLOPROTEASE

作品数:24被引量:31H指数:3
导出分析报告
相关领域:医药卫生更多>>
相关作者:高志鑫周顺张敏刘丽赖维更多>>
相关机构:中国海洋大学青岛农业大学中山大学附属第三医院新乡医学院更多>>
相关期刊:《Chinese Medical Journal》《Signal Transduction and Targeted Therapy》《Chinese Journal of Chemical Engineering》《Cellular & Molecular Immunology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划现代农业产业技术体山东省现代农业产业技术体系创新团队建设专项资金系建设专项资金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Targeting a disintegrin and metalloprotease(ADAM)17-CD122 axis enhances CD8^(+)T cell effector differentiation and anti-tumor immunity
《Signal Transduction and Targeted Therapy》2024年第7期3097-3111,共15页Lina Sun Anjun Jiao Haiyan Liu Renyi Ding Ning Yuan Biao Yang Cangang Zhang Xiaoxuan Jia Gang Wang Yanhong Su Dan Zhang Lin Shi Chenming Sun Aijun Zhang Lianjun Zhang Baojun Zhang 
supported by grants from the National Key Research and Development Program of China 2021YFA1100702(to B.Z.);National Natural Science Foundation of China grants 82271792(to L.S.),32200727(to L.S.)and 82071828(to C.S.);Innovation Capability Support Program of Shaanxi Province 2024CX-GXPT-45(to C.S.);Natural Science Foundation of Shaanxi Province 2017JM8148(to Lin Shi);Fundamental Research Funds for the Central Universities xtr072022002(to B.Z.);the National Natural Science Foundation of China 82350114(to L.Z.);the Natural Science Foundation Outstanding Youth Fund of Jiangsu Province BK20220049(to L.Z.);Suzhou Municipal Key Laboratory SZS2023005(to L.Z.).
CD8^(+)T cell immune responses are regulated by multi-layer networks,while the post-translational regulation remains largely unknown.Transmembrane ectodomain shedding is an important post-translational process orchest...
关键词:immunity stimulation INVOLVEMENT 
去整合素金属蛋白酶10和高迁移率族蛋白B1在声门型喉癌患者中的表达及预后分析
《中国耳鼻咽喉头颈外科》2023年第10期668-670,共3页孙亚萍 朱萍 朱晓燕 
南京市卫生科技发展专项(YKK22185)。
目的探讨去整合素金属蛋白酶10(a disintegrin and metalloprotease 10,ADAM10)和高迁移率族蛋白B1(high mobility group box-1 protein,HMGB1)与声门型喉癌患者病理特征及预后关系分析。方法回顾性收集2017年3月~2020年12月于南京医科...
关键词:喉肿瘤(Laryngeal Neoplasms) 预后(Prognosis) 去整合素金属蛋白酶10(a disintegrin and metalloprotease 10) 高迁移率族蛋白B1(high mobility group box-1 protein) 病理特征(pathological characteristics) 
Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke被引量:2
《Neural Regeneration Research》2023年第5期1033-1039,共7页Xiao-Wei Cao Hui Yang Xiao-Mei Liu Shi-Ying Lou Li-Ping Kong Liang-Qun Rong Jun-Jun Shan Yun Xu Qing-Xiu Zhang 
supported by the National Natural Science Foundation of China,Nos. 82071304 (to QXZ), 81671149 (to QXZ),and 81971179 (to XML);the Natural Science Foundation of Jiangsu Province,Nos. BK20191463 (to XML) and BK20161167 (to QXZ)。
We previously reported that postsynaptic density-93 mediates neuron-microglia crosstalk by interacting with amino acids 357–395 of C-X3-C motif chemokine ligand 1(CX3 CL1) to induce microglia polarization. More impor...
关键词:a disintegrin and metalloprotease domain 17 cerebral ischemia/reperfusion C-X3-C motif chemokine ligand 1 GW280264x microglia neuroinflammation postsynaptic density-93 Tat-CX3CL1(357–395aa) 
Cloning of catalase gene and antioxidant genes in Scophthalmus maximus response to metalloprotease of Vibrio anguillarum stress被引量:1
《Journal of Oceanology and Limnology》2022年第1期322-335,共14页Hai REN Jian LI Ping LIU Xianyun REN Tao SONG Guisheng GAO Duwen LI Shuaiting LIU 
Supported by the National Natural Science Foundation of China(No.31502187);the Natural Science Foundation of Hebei Province(No.C2018407049);the Hebei Provincial Department of Science and Technology(Nos.20286701Z,20567621H);the Talent Engineering Training Funding Project of Hebei Province(No.A201901057)。
Metalloproteases represent a class of extracellular proteases found in Vibrio anguillarum that can generate toxic and pathogenic eff ects in turbot(Scophthalmus maximus).The toxicological eff ect partly results from o...
关键词:gene cloning EXPRESSION reactive oxygen species METALLOPROTEASE head kidney cells 
An in vitro and in silico study of anti-dermatophytic activity of gossypol from fruits of Thespesia populnea(L.)Sol.ex Correa
《Asian Pacific Journal of Tropical Biomedicine》2021年第12期543-552,共10页Anuthara R Sebastian Jose Midhun Jyothis Mathew 
Objective:To isolate,purify,and characterize gossypol from the fruits of Thespesia populnea(L)Sol.ex Correa,test its antidermatophytic activity,identify its targets on the dermatophyte,and confirm the binding of gossy...
关键词:Thespesia populnea GOSSYPOL Anti-dermatophytic activity Trichophyton mentagrophytes Mechanism of action Gene expression Molecular docking METALLOPROTEASE MEP4 Isocitrate lyase ICL 
The M43 domain-containing metalloprotease RcMEP1 in Rhizoctonia cerealis is a pathogenicity factor during the fungus infection to wheat
《Journal of Integrative Agriculture》2020年第8期2044-2055,共12页PAN Li-jun LU Lin LIU Yu-ping WEN Sheng-xian ZHANG Zeng-yan 
funded by the Key Sci-Tech Program of China(2016ZX08002-001-004)。
Wheat(Triticum aestivum L.)is an important staple crop for global human.The necrotrophic fungus Rhizoctonia cerealis is the causal pathogen of sharp eyespot,a devastating disease of wheat.Herein,we identified RcMEP1,a...
关键词:cell death METALLOPROTEASE Rhizoctonia cerealis PATHOGENICITY WHEAT 
创伤弧菌和副溶血弧菌双重LAMP检测方法的建立及初步应用被引量:4
《中国兽医学报》2016年第11期1875-1881,共7页周顺 高志鑫 张敏 
山东省农业重大应用技术创新项目;山东省现代农业产业技术体系鱼类产业创新团队项目
为建立创伤弧菌和副溶血弧菌的双重环介导等温扩增(loop—mediated isothermal amplification,LAMP)检测方法,本试验以创伤弧菌metalloprotease基因和副溶血弧菌ompA基因为靶点设计LAMP扩增引物,并在内引物间添加不同的酶切位点,...
关键词:创伤弧菌 metalloprotease基因 副溶血弧菌 ompA基因 双重LAMP 
Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration被引量:7
《Cell Research》2016年第8期886-900,共15页Zhenyu Cai Anling Zhang Swati Choksi Weihua Li Tao Li Xue-Min Zhang Zheng-Gang Liu 
Necroptosis is a programmed, caspase-independent cell death that is morphologically similar to necrosis. TNF-induced necroptosis is mediated by receptor-interacting protein kinases, RIP1 and RIP3, and the mixed lineag...
关键词:MLKL ADAM metalloprotease NECROPTOSIS INFLAMMATION 
Effect of silencing a disintegrin and metalloprotease 12 expression on self-renewal capacity of CD133 positive giloma cells
《China Medical Abstracts(Internal Medicine)》2016年第2期58-59,共2页刘波 
Objective To investigate the inhibitory effect of a disintegrin and metalloprotease 12 silenced by shR-NA on self-renewal capacity of CD133 positive giloma cells.Methods The shRNA recombinant lentivirus aimed at silen...
关键词:RENEWAL SILENCING glioma ADAM aimed assigned spheres enriched suppress PRESSION 
解聚素金属蛋白酶17及变异型分化簇44在喉癌和喉咽癌组织中的表达
《中国耳鼻咽喉头颈外科》2014年第12期651-652,共2页张嫄 龚正鹏 
喉癌约占头颈恶性肿瘤的7.9%~35%[1],喉咽癌约占头颈部恶性肿瘤的1.4%~5.0%[1]。解聚素金属蛋白酶17(A disintegrin and metalloprotease 17,ADAM17),最初由Black等[2]和Moss等[3]两个独立的小组同时发现,又称肿瘤坏死因子α转换酶(t...
关键词:喉肿瘤(Laryngeal Neoplasms) 下咽肿瘤(Hypopharyngeal Neoplasms) 免疫组织化学(Immunohistochemistry) 解聚素金属蛋白酶17(disintegrin and METALLOPROTEASE 17) 
检索报告 对象比较 聚类工具 使用帮助 返回顶部