云南高校图书馆联盟文献共享服务平台- GENOMIC

GENOMIC: 作品数：732被引量：1696H指数：16; 导出分析报告; 相关领域：生物学农业科学更多>>; 相关作者：张丽杨新泉孙其信刘旺清韩宗福更多>>; 相关机构：中国农业大学清华大学华中农业大学吉林大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Prediction of genomic biomarkers for endometriosis using the transcriptomic dataset: 《World Journal of Clinical Cases》2025年第20期6-19,共14页Zeynep Kucukakcali Sami Akbulut Cemil Colak; approved by the Inonu University institutional review board for noninterventional studies(Approval No:2022/3842).; BACKGROUND Endometriosis is a clinical condition characterized by the presence of endometrial glands outside the uterine cavity.While its incidence remains mostly uncertain,endometriosis impacts around 180 million wom...; 关键词：ENDOMETRIOSIS RNA-SEQ TRANSCRIPTOMICS Machine learning Classification

The genomic and epigenomic landscape of iridocorneal endothelial syndrome: 《Genes & Diseases》2025年第3期523-532,共10页Yaoming Liu Gen Li Jiaxuan Jiang Sujie Fan Lan Lu Ting Wang Guigang Li Wenzong Zhou Xuequn Liu Yingjie Li Hong Sun Liang Liang Yuhong Tang Yang Chen Jianjun Gu Fei Li Xiuli Fang Tao Sun Aiguo Lv Yayi Wang Peiyuan Wang Tao Wen Jiayu Deng Yuhong Liu Mingying Lai Jingni Yu Danyan Liu Hua Wang Meizhu Chen Li Li Xiaodan Huang Jingming Shi Xu Zhang Kang Zhang Lingyi Liang Xiulan Zhang; supported by the National Key Research and Development Program of China(No.2022YFC2502800);the National Natural Science Foundation of China(No.82070955,32000537).; Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding eye diseasewith an unknown etiology. Understanding its genomic and epigenomic landscape could aid indeveloping etiology-based therapies. In this...; 关键词：Copy number variance DNA methylation ETIOLOGY Iridocorneal endothelial syndrome Whole-genome sequencing

A novel research model of clonal evolution in mantle cell lymphoma at the single-cell genomic level: 《Genes & Diseases》2025年第3期35-38,共4页Li Zhang Yongsheng Liu Liang Wang Li Wang Li Zheng Wei He Li Yan Lvsu Ye Huidan Zhang Junling Tang; funded by the Chongqing Medical Scientific Research Project(Joint Project of Chongqing Health Commission and Science and Technology Bureau,China)(No.2023GGXM006,2024ZDXM026,2024MSXM115);the Key Research Project from Science and Technology Department of Sichuan Province,China(No.2019YFS0301);the Chongqing Key Municipal Public Health Specialty Construction Project(China);the Key Research Project from Chongqing Medical and Pharmaceutical Vocational Education Group(China)(No.CQZJ202329);the Incubation Project of the First Affiliated Hospital of Chongqing Medical and Pharmaceutical College(China)(No.2022-2023ZD04,2022-2023ZD03,2022-2023MS04,2022-2023MS03,2022-2023MS010);the Science and Technology Research Program of Chongqing Education Commission(China)(No.KJQN202302811).; Mantle cell lymphoma(MCL)is recognized as one of the most genetically heterogeneous diseases,with high instability at the genomic level.MCL is common in males with a male-to-female ratio of about 2:1,and its incidence...; 关键词：hematopoietic lineage mantle cell lymphoma mcl clonal evolution genomic instability tumor immunity evolution tree single cell genomic level genetic heterogeneity mantle cell lymphoma

Cholestasis in hepatitis E virus infection: 《World Journal of Hepatology》2025年第4期1-6,共6页Tatsuo Kanda Reina Sasaki-Tanaka Takeshi Yokoo Kazunao Hayashi Hiroteru Kamimura Atsunori Tsuchiya Shuji Terai; Supported by the Japan Agency for Medical Research and Development(AMED),No.JP24fk0210132(Kanda T,Sasaki-Tanaka R and Terai S);the JSPS KAKENHI,No.JP23K15055(Sasaki-Tanaka R).; Hepatitis E virus(HEV)infection causes acute hepatitis,chronic hepatitis,particularly in compromised hosts,and various extrahepatic manifestations.HEV infection is reportedly associated with biliary-pancreatic disease...; 关键词：Genomic mutations CHOLESTASIS Farnesoid X receptor Hepatitis E virus JAUNDICE

Genomic Characterization of BvMLO Genes in Sugar Beet Focusing on BvMLO2 BvMLO7 Responses to Cercospora beticola and Abiotic Stress: 《Phyton-International Journal of Experimental Botany》2025年第3期875-895,共21页Ran Li Liuhong Chen Yu Liu Chunlei Zhao Yanli Li Guangzhou Ding; Mildew resistance locus O(MLO)proteins are extensively found in various plant species and are essential for multiple biological functions.The characterization and analysis of MLO genes have been conducted across numer...; 关键词：Beta vulgaris L. BvMLO family Cercospora leaf spot(CLS) expression profile abiotic stress

Physicians'risk and time preferences and their willingness to detect and disclose genomic secondary findings:A multiple price list experiment: 《Pharmacoeconomics and Policy》2025年第1期25-32,共8页Shan Jiang Haiyin Wang Zhuo Chen Xiao Zang Yawen Jiang Zhongliang Zhou Yuanyuan Gu; To quantify physicians'risk and time preferences and explore the association between the preferences and their willingness to detect and disclose secondary findings(SFs)derived from genome-scale sequencing.We designed...; 关键词：Risk preference Time preference Behavioural economics Secondary findings Genome sequencing

CRISPR/Cas genome editing for cotton precision breeding:mechanisms,advances,and prospects: 《Journal of Cotton Research》2025年第1期115-128,共14页SHERI Vijay MOHAN Harikrishnan JOGAM Phanikanth ALOK Anshu ROHELA Gulab Khan ZHANG Baohong; supported by the Cotton Incorporated.; Cotton(Gossypium hirsutum L.)is one of the most important global crops that supports the textile industry and pro-vides a living for millions of farmers.The constantly increasing demand needs a significant rise in cot...; 关键词：CRISPR/Cas Biotic stress Fiber quality Genomic complexity Off-target effects Textile industry

GEFormer:A genotype-environment interactionbased genomic prediction method that integrates the gating multilayer perceptron and linear attention mechanisms: 《Molecular Plant》2025年第3期527-549,共23页Zhou Yao Mengting Yao Chuang Wang Ke Li Junhao Guo Yingjie Xiao Jianbing Yan Jianxiao Liu; supported by the Biological Breeding-National Science and Technology Major Project(2023ZD04076);the Hubei Provincial Natural Science Foundation(2023AFB832),the Natural Science Foundation of Guizhou Province Science and Technology Agency(ZK[2025]096);the Major Project of Hubei Hongshan Laboratory(2022HSZD031);the Yingzi Tech&Huazhong Agricultural University Intelligent Research Institute of Food Health(IRIFH202209).; The integration of genotypic and environmental data can enhance genomic prediction accuracy for crop field traits.Existing genomic prediction methods fail to consider environmental factors and the real growth environm...; 关键词：genomic prediction crop growth environment genotype-environment interactions gated MLP linear attention mechanism

Toward understanding the role of genomic repeat elements in neurodegenerative diseases: 《Neural Regeneration Research》2025年第3期646-659,共14页Zhengyu An Aidi Jiang Jingqi Chen; supported by the National Natural Science Foundation of China, No.61932008;Natural Science Foundation of Shanghai, No.21ZR1403200 (both to JC)。; Neurodegenerative diseases cause great medical and economic burdens for both patients and society;however, the complex molecular mechanisms thereof are not yet well understood. With the development of high-coverage se...; 关键词：Alzheimer's disease ATAXIA deep learning long-read sequencing NEURODEGENERATION neurodegenerative diseases Parkinson's disease repeat element structural variant

TCF3 as a multidimensional biomarker:oncogenicity,genomic alterations,and immune landscape in pan-cancer analysis: 《Acta Biochimica et Biophysica Sinica》2025年第2期195-208,共14页Huiling Nie Yang Yu Siqi Zhou Yue Xu Xi Chen Xun Qin Zhangyu Liu Jiayu Huang Hailiang Zhang Jin Yao Qin Jiang Bingbing Wei Xiaojian Qin; supported by the grants from the National Natural Science Foundation of China(Nos.82171074,81970809 and 81570859);the Suzhou Medical Innovation Application Research Project(No.SZM2023027).; Transcription factor 3(TCF3),a pivotal member of the TCF/LEF family,plays a critical role in tumorigenesis.Nonetheless,its impact on the tumor microenvironment(TME)and cancer phenotypes remains elusive.We perform an e...; 关键词：TCF/LEF family TCF3 pan-cancer analysis prognosis tumor microenvironment(TME) epithelial-mesenchymal transition(EMT)

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