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作品数：856被引量：1602H指数：14
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相关机构：北京大学南方医科大学沈阳药科大学中国医科大学更多>>
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A macro-transection model of brain trauma for neuromaterial testing with functional electrophysiological readouts
《Neural Regeneration Research》2025年第12期3539-3552,共14页Jessica Wiseman Raja Haseeb Basit Akihiro Suto Sagnik Middya Bushra Kabiri Michael Evans Vinoj George Christopher Adams George Malliaras Divya Maitreyi Chari 
supported by awards from the EPSRC Centre for Doctoral Training in Regenerative Medicine(EP/L014904/1,to JW);an NHS bursary(to RHB);an EPSRC Healthcare Technologies award(EP/T013885/1,to DMC)。
Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies.Biomaterial therapies show promise as medical materials for neural repair through immunomodulation,struct...
关键词：in vitro modelling multielectrode array interfacing nanoparticles neuromaterials scratch assay transecting injury traumatic brain injury 
Comprehensive discovery and functional characterization of the noncanonical proteome
《Cell Research》2025年第3期186-204,共19页Chengyu Shi Fangzhou Liu Xinwan Su Zuozhen Yang Ying Wang Shanshan Xie Shaofang Xie Qiang Sun Yu Chen Lingjie Sang Manman Tan Linyu Zhu Kai Lei Junhong Li Jiecheng Yang Zerui Gao Meng Yu Xinyi Wang Junfeng Wang Jing Chen Wei Zhuo Zhaoyuan Fang Jian Liu Qingfeng Yan Dante Neculai Qiming Sun Jianzhong Shao Weiqiang Lin Wei Liu Jian Chen Liangjing Wang Yang Liu Xu Li Tianhua Zhou Aifu Lin 
funded by Noncommunicable Chronic Diseases-National Science and Technology Major Project(2023ZD0507500);the National Science Fund for Distinguished Young Scholars(32225014);"Lingyan"R&D Project(2023C03023);the National Key R&D Program of China(2021YFC2700903);the National Natural Science Foundation of China(81672791 and 81872300);Zhejiang Provincial Natural Science Fund for Distinguished Young Scholars of China(LR18C060002);the Fundamental Research Funds for the Central Universities(K20220228);the Young Scientists Fund of the National Natural Science Foundation of China(8240112554);the Medical Science and Technology Project of Zhejiang Province(WKJ-ZJ-2310).
The systematic identification and functional characterization of noncanonical translation products,such as novel peptides,will facilitate the understanding of the human genome and provide new insights into cell biolog...
关键词：reference library ultrafiltration tandem mass spectrometry open reading frames ultrafiltration tandem mass spectrometry assay gastric tiss noncanonical proteome understanding human genome cell biologyherewe 
Using protein turnover assay to explore the drug mechanism of Carfilzomib
《Acta Biochimica et Biophysica Sinica》2025年第2期209-222,共14页Yonghui Tao Xinyu Ding Caiwei Jia Chengcheng Wang Chuanyin Li 
supported by the grants from the Shanghai Sailing Program(19YF1444700);the National Natural Science Foundation of China(Nos.31900804 and 82304563);the Guizhou Province Science and Technology Foundation([2020]1Y086);the Science and Technology Foundation of Guizhou Provincial Health Commission(No.gzwkj2022-219).
Carfilzomib(CFZ)is the second-generation proteasome inhibitor that is approved by Food and Drug Administration(FDA)of USA for the treatment of relapsed and refractory multiple myeloma.Although the preclinical and clin...
关键词：Carfilzomib multiple myeloma PROFILING protein homeostasis 
On-site visual detection of Nipah virus combining a reverse transcription recombinase-aided amplification with a lateral-flow dipstick assay
《Journal of Integrative Agriculture》2025年第2期790-794,共5页Kaikai Jin Junjie Zhao Huanxin Chen Zimo Zhang Zengguo Cao Zanheng Huang Hao Li Yongsai Liu Lisi Ai Yufei Liu Changqi Fan Yuanyuan Li Pei Huang Hualei Wang Haili Zhang 
supported by the National Key Research and Development Program of China(2021YFF0703600)。
Highlights The RT-RAA-VF assay developed for the NiV P gene can perform rapid detection of NiV within 20 min at 42℃ with high specificity.This assay is capable of attaining sensitivity to a single copy of NiV RNA tra...
关键词：Singh destroyed visual 
Interferon Gamma Release Assay for Latent Tuberculosis Screening in High TB-Endemic Region: A Retrospective Study
《Journal of Tuberculosis Research》2024年第4期183-192,共10页Shaheda Anwar Ahmed Abu Saleh SM Ali Ahmed Saika Farook Farhan Muhib Udoy Maisha Islam Tanvir Ahmed Siddiqui Md Sultan Ahmed 
Introduction: Tuberculosis (TB) remains a significant public health challenge, particularly in high-endemicity settings where latent TB infections (LTBI) contribute to ongoing transmission. Early identification and ma...
关键词：Latent Tuberculosis Infection (LTBI) Interferon-Gamma Release Assay (IGRA) High Endemicity Regions LTBI Risk Factors 
Development and evaluation of a RT-RAA-combined CRISPR/Cas12a assay for the detection of African horse sickness virus
《Journal of Integrative Agriculture》2024年第12期4267-4271,共5页Yingzhi Zhang Lei Na Kui Guo Jinhui Wang Zhe Hu Cheng Du Xuefeng Wang Xiaojun Wang 
supported by the National Key Research and the Development Project of China(2022YFD1800504);the Natural Science Foundation of Heilongjiang Province of China(TD2022C006)。
African horse sickness(AHS)is an acute and fatal vectorborne infectious disease of equids,caused by the African horse sickness virus(AHSV).The World Organization for Animal Health(WOAH)has classified AHS as a notifiab...
关键词：HAS HORSE SICKNESS 
Study on Performance Parameters of ATP Bioluminescence Detection Technology for Hand Surface Cleanliness
《Chinese Journal of Biomedical Engineering(English Edition)》2024年第4期153-157,共5页CHEN Xiong WANG Tao LIN Zhen XIE Zhi-min CHEN Xiang 
Objective:To evaluate the performance parameters of adenosine triphosphat(ATP)bioluminescence detection technology in assessing surface cleanliness in surgical environments and on hand surfaces.Methods:Samples were co...
关键词：adenosine triphosphat(ATP)bioluminescence assay CLEANLINESS hand hygiene surgical environment INSTRUMENTS 
Analysis of HTLV Infection Status among Voluntary Blood Donors in Yulin City
《Advances in Infectious Diseases》2024年第4期838-846,共9页Xuefeng Mao Rong Ren Yumei Tan Fengping Chen Xinfeng Du Zhencai Gu 
Objective: To comprehensively understand the infection status of human T-lymphotropic virus (HTLV) among the voluntary blood donors in Yulin City and accurately assess the impact of HTLV on the current situation of bl...
关键词：Human T-Lymphotropic Virus Enzyme-Linked Immunosorbent Assay Immunoblotting Assay Real-Time Fluorescent Quantitative Polymerase Chain Reaction 
Nitrogen-doped carbon dots as efficient turn-on fluorescent probe for assay of organophosphorus pesticides
《ChemPhysMater》2024年第4期462-469,共8页Jiqing Zhang Shushu Chu Chenyu Tao Jinghao Yan Yuanyuan Jiang Yizhong Lu 
supported by the National Natural Science Foundation of China(22172063 and 21902062);Young Taishan Scholar Program(tsqn201812080);Independent Cultivation Program of Innovation Team of Ji’nan City(2021GXRC052).
Concerns regarding human health and food safety have generated interest in developing simple,accurate,and cost-effective strategies for evaluating organophosphorus pesticide(OP)residues.In this study,nitrogen-doped ca...
关键词：Nitrogen-doped carbon dots Alkaline phosphatase Organophosphorus pesticides Logic gates Fluorescence imaging 
Long-term fallowing produces specific fungal taxa associated with soil carbon storage
《Pedosphere》2024年第6期1014-1025,共12页Fang LI Lin CHEN Yue LI Yanlai HAN Yi WANG Peipei LI Shuiqing ZHANG Jiabao ZHANG 
supported by the Excellent Youth Science Fund of Henan Province,China(No.242300421147);the National Key Research and Development Program of China(No.2022YFD1500203);the National Natural Science Foundation of China(Nos.42377334 and 42007005);the Joint Fund Project of Henan Province,China(No.232103810009)。
Cropland expansion has caused the loss of soil organic carbon(SOC)and the degradation of microbial communities.Fallowing is an important strategy for soil restoration,and fungi are critical in soil fertilization.This ...
关键词：^(13)C-labelling assay Chaetomiaceae CO_(2)fixation long-term fertilization microbial species resources soil fungal community soil organic C Trichocladium 
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