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Remote sensing of liquid cloud profiles based on an analytical cloud profiling model: 《Science China Earth Sciences》2025年第4期998-1012,共15页Huazhe SHANG Husi LETU Lesi WEI Run MA Yutong WANG Zhaoxin CAI Shuai YIN Chong SHI; supported by the National Natural Science Foundation of China(Grant Nos.42025504,42175152&42405145);the National Key Research and Development Program of China(Grant No.2023YFB3905900);the Youth Innovation Promotion Association of Chinese Academy of Sciences(Grant No.2021122);the Science and Disruptive Technology Program,AIRCAS(Grant No.E2Z202020F);the Natural Science Foundation of Sichuan Province(Grant No.2024NSFSC0770)。; The characteristics of microphysical profiles of liquid clouds(i.e.,the cloud effective radius(ER)and liquid water content(LWC))are important factors in understanding the aerosol-cloud-precipitation process and improv...; 关键词：Analytical cloud profiling model Cloud effective radius Cloud liquid water content CLOUDSAT Airborne mea-surements

Metabolomic profiling and prognostication in CoVID-19 acute respiratory distress syndrome: 《Journal of Intensive Medicine》2025年第1期108-110,共3页David Furfaro Xiaoyu Che Wenhao Gou Matthew J.Cummings Nischay Mishra Daniel Brodie Thomas Briese Oliver Fiehn W.Ian Lipkin Max R.O'Donnell; CHEST Foundation Grant in COVID-192020(DMF).; To the Editor,Coronavirus disease 2019(COVID-19)-related acute respiratory distress syndrome(ARDS)is biologically and clinically heterogeneous with a broad spectrum of organ dysfunction and illness severity.[1] In COV...; 关键词：DISTRESS ACUTE Metab

Profiling the cell diversity and tissue structure of aqueous humor circulatory system in human eyes using spatial single-cell RNA sequencing: 《Genes & Diseases》2025年第1期56-59,共4页Hao Yuan Zhaona Song Xiao Sun Chunping Song Lidong Guo Qiang Zhang Yonglun Luo Chengfu Yuan Jianlu Gao Xiaodong Jia; supported by grants from the Natural Science Foundation of Shandong Province,China(No.ZR2019QH009).; Elevated intraocular pressure(IOP)is recognized as a significant contributor to the development of various ocular diseases,especially glaucoma.The delicate balance between the generation and drainage of aqueous humor(...; 关键词：structure thereby INCOMPLETE

Pattern-based rapid and robust profiling of gut microbiota and its metabolism with a single fluorescent probe: 《Science China Chemistry》2025年第2期781-788,共8页Hongli Tan Meizi Zeng Cong Fang Xiaohua Zhu Feng Liu Ying Long Ruijie Deng Peng Yin Meiling Liu Haitao Li Youyu Zhang Shouzhuo Yao; supported by the National Natural Science Foundation of China(22376057,22274048,22274045,22074100,22274047,22104033);the Foundation of the Science&Technology Department of Hunan Province(2021ZJ1123,2023JJ30394);support from China Postdoctoral Science Foundation(2023M731053)。; The gut microbiota and the associated metabolism play a pivotal role in maintaining human health,yet their assessment is challenging due to their inherent diversity,variety,and complexity.Herein,we developed a multich...; 关键词：gut microbiota biological thiols sensor array fluorescent probe

Design and Application of Turbine Cascade Partitioned Endwall Profiling: 《Journal of Thermal Science》2025年第1期110-128,共19页ZENG Fei JIANG Ruiqi XUE Xingxu DU Wei LUO Lei ZHOU Xun; the financial support provided by the National Science and Technology Major Project(J2019-Ⅳ-0008-0076,No.2019-Ⅱ-0010-0030);Natural Science Fund for Excellent Young Scholars of Heilongjiang Province(No.YQ2021E023)。; The influence of partitioned profiling design based on a large-pitch highly loaded cascade is studied by numerical simulation.The partitioned profile is mainly composed of a pressure-side convex structure near the lea...; 关键词：large-pitch highly loaded cascade highly loaded design non-axisymmetrical endwall design secondary flow control partitioned endwall profiling

Using protein turnover assay to explore the drug mechanism of Carfilzomib: 《Acta Biochimica et Biophysica Sinica》2025年第2期209-222,共14页Yonghui Tao Xinyu Ding Caiwei Jia Chengcheng Wang Chuanyin Li; supported by the grants from the Shanghai Sailing Program(19YF1444700);the National Natural Science Foundation of China(Nos.31900804 and 82304563);the Guizhou Province Science and Technology Foundation([2020]1Y086);the Science and Technology Foundation of Guizhou Provincial Health Commission(No.gzwkj2022-219).; Carfilzomib(CFZ)is the second-generation proteasome inhibitor that is approved by Food and Drug Administration(FDA)of USA for the treatment of relapsed and refractory multiple myeloma.Although the preclinical and clin...; 关键词：Carfilzomib multiple myeloma PROFILING protein homeostasis

GC-MS Profiling,In Vitro and In Silico Antibacterial and Antioxidant Potential of Origanum elongatum Essential Oil:Novel Source against Phytopathogenic Bacteria: 《Phyton-International Journal of Experimental Botany》2025年第2期481-501,共21页Amine Batbat Mohamed El Fadili Naoufal El Hachlafi Amine Elbouzidi Chaymae Hmimen Hiba Yahyaoui Samir Jeddi Abdellatif Benbouazza Kawtar Fikri-Benbrahim Mohamed Addi Samiah Hamad Al-Mijalli Khaoula Habbadi Hassane Greche; This study highlights the regulatory potential antibacterial and antiradical of Origanum elongatum essential oil(EO),an endemic medicinal plant of Morocco used for its various properties.The chemical composition of th...; 关键词：Origanum elongatum medicinal plant chemical composition biological activity antiradical activity molecular docking

A dual-excitation-driven full-component-responsive lanthanide-basedmetal-organic framework for switchable profiling of multi-diseasemarkers: 《Science China Materials》2025年第2期666-676,共11页Guoli Chen Bin Dai Ji-Na Hao Yongsheng Li; supported by the National Key Research and Development Program of China (2022YFC2403203, 2024YFF0508601);the National Natural Science Foundation of China (52172279);the Basic Research Program of Shanghai (21JC1406003);the Shanghai Rising-Star Program (21QA1402200);the Leading Talents in Shanghai in 2018, the Key Field Research Program (2023AB054);the Higher Education Discipline Innovation Project (B14018)。; Accurate detection of multiple small end-metabolic biomarkers is more sensitive than large biomoleculesto provide real-time feedbacks of physiological/pathologicalstate, but is more challenging due to lack of specific...; 关键词：luminescent probes lanthanide-based metal-organic frameworks dual-excitation regulation multi-disease markers detection

Transcriptome and single-cell profiling of the mechanism of diabetic kidney disease: 《World Journal of Diabetes》2025年第2期216-236,共21页Ying Zhou Xiao Fang Lin-Jing Huang Pei-Wen Wu; Joint Funds for the Innovation of Science and Technology,Fujian Province,No.2021Y9106;Fujian Provincial Health Technology Project,No.2021GGA033;the Natural Science Foundation of Fujian Province,No.2024J011234.; BACKGROUND The NOD-like receptor thermal protein domain associated protein 3(NLRP3)inflammasome may play an important role in diabetic kidney disease(DKD).However,the exact link remains unclear.AIM To investigate the ...; 关键词：Diabetic kidney disease Single-cell RNA sequencing analysis NOD-like receptor thermal protein domain associated protein 3 Sirtuin 2 Caspase 1

Ribosome profiling and single-cell RNA sequencing identify the unfolded protein response as a key regulator of pigeon lactation: 《Zoological Research》2025年第1期54-74,共21页Jing Liu San-Feng Liu Hui-Rong Mao Hong-Xia Jiang Shui-Bing Liu Xiao-Fei Xu Jin-Tao Wu Xun Liu Wen-Tao Zhang Xiao-Long Hu Biao Chen; supported by the Department of Agriculture and Rural Affairs of Jiangxi Province,China (JXARS-09);Science and Technology Program of Guangdong Province,China (2020B1212060060)。; Pigeons and certain other avian species produce a milklike secretion in their crop sacs to nourish offspring,yet the detailed processes involved are not fully elucidated.This study investigated the crop sacs of 225-da...; 关键词：PIGEON Crop lactation Secretory epithelial cells Single-cell RNA sequencing Ribosome profiling Signaling pathway

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