Endogenous sulfur dioxide is a new gasotransmitter with promising therapeutic potential in cardiovascular system  

内源性二氧化硫是心血管系统新的具有治疗前景的气体信号分子

作　　者：Yaqian Huang Heng Zhang Boyang Lv Chaoshu Tang Junbao Du Hongfang Jin 黄娅茜;张恒;吕博洋;唐朝枢;杜军保;金红芳(Department of Pediatrics,Peking University First Hospital,Beijing 100034,China;Department of Endocrinology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China;Department of Physiology and Pathophysiology,Peking University Health Science Center,Beijing 100191,China;Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education,Beijing 100191,China)

机构地区：[1]Department of Pediatrics,Peking University First Hospital,Beijing 100034,China [2]Department of Endocrinology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China [3]Department of Physiology and Pathophysiology,Peking University Health Science Center,Beijing 100191,China [4]Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education,Beijing 100191,China

出　　处：《Science Bulletin》2021年第16期1604-1607,共4页科学通报（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(81770422,81921001,81970424,81770278,and 82070445);the Beijing Natural Science Foundation(7182168,7191012,and 7171010);Changjiang Scholar Program of Ministry of Education of China(Q2017004).

摘　　要：Sulfur dioxide(SO_(2))was previously considered only as air pollutant.In 2008,our group first detected the endogenous SO_(2)gener-ating enzymes as well as its generating pathway in cardiovascular system[1].Our recent studies have shown that endogenous SO_(2)plays important cardiovascular physiologic regulatory roles and has pathophysiological significance.As such,we suggested that it serves as a new gasotransmitter[1-4].

关 键 词：气体信号分子 GENERATING dioxide 

分 类 号：R914[医药卫生—药物化学]