乳腺癌保乳手术标本的病理取材与安全切缘评估  

Assessment of pathological biopsy and safety margin of specimens from breast cancer patients with breast conversing surgery

作　　者：吕鉴可 杨壹羚 付丽 Lyu Jianke;Yang Yiling;Fu Li(Department of Breast Pathology,Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center of Cancer National Key Discipline of Pathology Breast Cancer Research Innovation Team,Ministry of Education Tianjin′s Key Laboratory of Cancer Prevention and Therapy Tianjin′s Clinical Research Center for Cancer Key Laboratory of Breast Prevention and Therapy,Ministry of Education,Tianjin 300060,China)

机构地区：[1]天津医科大学肿瘤医院乳腺病理研究室,国家肿瘤临床医学研究中心,国家病理学重点学科,教育部乳腺癌防治研究创新团队,天津市肿瘤防治重点实验室,天津市恶性肿瘤临床医学研究中心,乳腺癌防治教育部重点实验室,300060

出　　处：《中华肿瘤杂志》2021年第8期817-820,共4页Chinese Journal of Oncology

基　　金：国家自然科学基金(81672637、81872164)。

摘　　要：保乳手术是早期乳腺癌治疗的重要手段之一。保乳手术标本的病理取材、安全切缘的病理诊断至关重要。目前,关于保乳手术切除标本的病理取材方法和癌阴性切缘诊断标准尚未统一。通过与美国MD Anderson癌症中心的保乳手术标本取材和诊断方法进行比较分析,总结了天津医科大学肿瘤医院乳腺病理科对早期乳腺癌保乳手术标本的病理取材和诊断方法,旨在从病理角度探讨如何准确反映保乳手术切缘的情况,为保乳手术的成功保驾护航。Breast-conserving surgery(BCS)has now become one of the optimal surgical choices for early invasive breast cancer.The pathological diagnosis of margin in breast-conserving specimen is very important.There is no acknowledge on the approaches of pathological biopsy and safety margin diagnosis of breast conserving surgery.This paper will compare the biopsy and diagnosis methods of breast-conserving surgery specimens between Tianjin Medical University Cancer Institute and Hospital in China and MD Anderson Cancer Center in the United States.We summarize our biopsy method and diagnostic criteria to explore how to accurately evaluate the margin of breast-conserving surgery specimen from a pathological point of view,and to escort a successful breast-conserving surgery.

关 键 词：乳腺肿瘤 保乳手术 取材方法 切缘评估 

分 类 号：R737.9[医药卫生—肿瘤]