Toric角膜塑形术对伴有中高度散光近视眼的角膜高阶像差的影响  

Effect of toric design orthokeratology on corneal high order aberration of myopia with moderate to high astigmatism

作　　者：郑帆 陈迎月 王峥 ZHENG Fan;CHEN Yingyue;WANG Zheng(Department of Ophthalmology,the Affiliated Fuzhou Municipal Second Hospital of Xiamen University,Fuzhou,Fujian 350007,China)

机构地区：[1]厦门大学附属福州第二医院眼科,福州350007 [2]福州眼科医院

出　　处：《福建医药杂志》2021年第4期4-7,共4页Fujian Medical Journal

基　　金：福州市科技计划社会发展项目(2018-S-101-5)。

摘　　要：目的观察伴有中高度散光的近视眼在Toric角膜塑形术后角膜高阶像差的变化,以及比较不同直径范围下的角膜高阶像差的改变情况。方法前瞻、随机选取36例(72眼)伴有中高度散光的近视患者,应用Pentacam眼前节分析系统测量其在Toric角膜塑形术前及塑形1个月后的高阶像差,分别记录角膜前后表面及全角膜的中央3mm、6mm直径的总高阶像差及3~6阶高阶像差。应用SPSS 19.0统计学软件进行数据分析。结果塑形术后角膜前、后表面中央6mm直径的总高阶像差及3~6阶像差的均方根值均明显增加,与塑形前相比差异均有统计学(P<0.05),角膜前表面高阶像差的增加值高于后表面,其中以4阶像差的改变量最大。塑形术后角膜前表面及全角膜的总高阶像差、3~6阶像差及角膜后表面的总高阶像差、3阶、4阶像差在中央6mm范围直径的增加量,较中央3mm范围直径的对应高阶像差增加量均更为显著,差异有统计学意义(P<0.05);塑形术后角膜后表面的5阶及6阶像差的增加量在中央6mm和3mm范围直径下差异无统计学意义(P>0.05)。结论Toric角膜塑形术前后,角膜前、后表面各项高阶像差均增大,角膜前表面高阶像差的变化是引起全角膜高阶像差变化的主要因素。角膜塑形术后,角膜前表面及全角膜的高阶像差在中央6mm范围表现出更大的改变。Objective To observe the changes of high order aberration(HOA)in myopia with moderate and high astigmatism after toric orthokeratology,and compare the variation of corneal HOA induced by orthokeratology in different measurement diameter.Methods A total of 36 cases(72 eyes)of myopia patients with moderate and high astigmatism were selected prospectively and randomly.The HOA before and one month after toric orthokeratology were measured by Pentacam,and the total HOA and 3-6 th order aberrations in central 3 mm and 6 mm diameter ranges on the anterior and posterior surfaces of cornea were recorded separately.The data were analyzed by SPSS 19.0 software.Results After orthokeratology,the root mean square(RMS)values of the total HOA and 3-6 th order aberrations within 6 mm measurement diameter in the center of the anterior and posterior corneal surface were increased significantly(P<0.05).There were more increment in all HOA on the anterior corneal surface than posterior corneal surface,and the 4 th order aberration showed the largest change.The variation of the total HOA and 3-6 th order aberrations within 6 mm measurement diameter on the anterior corneal surface and whole cornea were more significant than the corresponding aberrations within 3 mm range(P<0.05),so were the total HOA,3 rd order and 4 th order aberrations on the posterior corneal surface.There were no significant differences in increment of 5 th order,6 th order aberrations between 6 mm and 3 mm measurement range on posterior corneal surface(P>0.05).Conclusion Before and after toric orthokeratology,the corneal HOA increases,and the change of HOA on anterior corneal surface contributed more.The HOA of cornea in central 6 mm range shows greater variation.

关 键 词：角膜塑型术 高阶像差 近视 PENTACAM 

分 类 号：R778[医药卫生—眼科]