急性髓系白血病伴非典型Cogan综合征1例报告并文献复习  

Acute myeloid leukemia with atypical Cogan syndrome:A case report and literature review

作　　者：赵萌 赵岩[1] 李小丰[1] 任立参[1] 朱耿军[1] 李小霞 於秋燕 沈卫章[1] ZHAO Meng;ZHAO Yan;LI Xiaofeng

机构地区：[1]吉林大学第二医院肿瘤血液科,长春130041

出　　处：《临床血液学杂志》2021年第7期511-513,共3页Journal of Clinical Hematology

摘　　要：Cogan综合征是一种自身免疫性系统性血管炎性疾病,其发病率低。典型Cogan综合征以非梅毒性角膜基质炎和前庭-听觉系统受累为特征,而非典型形式临床表现多样,可有多个系统受累。由于我国缺乏此类疾病相关认识,其诊断率较低,在此我们报道1例急性髓系白血病伴非典型Cogan综合征病例,并通过文献复习讨论急性髓系白血病伴非典型Cogan综合征的诊断及治疗体会。Cogan syndrome is an autoimmune systemic vascular inflammatory disease with a low incidence. The typical Cogan syndrome is characterized by non syphilitic interstitial keratitis associated with vestibulo-auditory dysfunction, while the atypical form is diverse in clinical manifestations and may involve multiple systems. Due to the lack of relevant knowledge in China, the diagnostic rate of such diseases is low. Here, we report a case of acute myeloid leukemia with atypical Cogan syndrome, review available research findings on how to diagnose and manage acute myeloid leukemia with atypical Cogan syndrome.

关 键 词：COGAN综合征 急性髓系白血病 糖皮质激素 化疗 

分 类 号：R733.71[医药卫生—肿瘤]