Nucleic acid detection in the diagnosis and prevention of schistosomiasis  

作　　者：Ping He Lan-gui Song Hui Xie Jin-yi Liang Dong-ya Yuan Zhong-dao Wu Zhi-yue Lv 

机构地区：[1]Department of Parasitology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China [2]Key Laboratory of Tropical Disease Control,Ministry of Education,Guangzhou 510080,China [3]Department of Pathogenic Biology,Medical School,Xizang Minzu University,Xianyang 712082,China

出　　处：《Infectious Diseases of Poverty》2016年第1期230-240,共11页贫困所致传染病（英文）

基　　金：supported by the National Major Scientific and Technological Special Project(no.2012ZX10004220);the National Natural Science Foundation of China(nos.81401688,81271855,81261160324,81371836,and 81572023)。

摘　　要：Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals.Surveillance and diagnosis play key roles in schistosomiasis control,however,current techniques for surveillance and diagnosis of the disease have limitations.As genome data for parasites are increasing,novel techniques for detection incorporating nucleotide sequences are receiving widespread attention.These sensitive,specific,and rapid detection methods are particularly important in the diagnosis of low-grade and early infections,and may prove to have clinical significance.This paper reviews the progress of nucleic acid detection in the diagnosis and prevention of schistosomiasis,including such aspects as the selection of target genes,and development and application of nucleic acid detection methods.

关 键 词：Schistosoma japonicum S.mansoni S.haematobium DIAGNOSIS Nucleic acid detection 

分 类 号：R73[医药卫生—肿瘤]