正念认知法联合抗抑郁药物对抑郁症患者认知功能和心理状态的影响  

The effect on the cognitive function and mental state of mindfulness cognition combined with antidepressants on patients with depression

作　　者：王佳慧 张振学 WANG Jiahui;ZHANG Zhenxue(Department of Affective Disorders,the Third People's Hospital of Fuyang,Fuyang,Anhui 236000,China)

机构地区：[1]阜阳市第三人民医院情感障碍科,安徽省阜阳市236000

出　　处：《中南医学科学杂志》2021年第5期551-554,共4页Medical Science Journal of Central South China

基　　金：安徽省卫生健康委科研项目(AHWJ2021a035)。

摘　　要：目的研究正念认知行为的团体治疗与抗抑郁药物治疗对抑郁症患者认知功能和心理状态的影响。方法选取抑郁症患者130例,随机均分为对照组和正念认知组。对照组予以常规抗抑郁药物治疗,正念认知组在对照组基础上进行正念认知行为的团体治疗,比较两组临床治疗疗效及汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、简易应对方式问卷(SCSQ)以及威斯康星卡片分类测试(WCST)。结果正念认知组治疗总有效率明显高于对照组(P<0.05)。与治疗前比较,治疗后两组HAMD、HAMA评分均降低,且正念认知组下降程度大于对照组(P<0.05);两组SCSQ评分均有所改善,且正念认知组改善程度大于对照组(P<0.05);两组WCST均有所改善,且正念认知组应答总数、非持续性错误应答数多于对照组(P<0.05),持续性错误应答数少于对照组(P<0.05)。结论正念认知行为的团体治疗联合抗抑郁药物治疗抑郁症患者,能有效促进患者认知功能恢复,改善对应方式,缓解患者焦虑及抑郁情绪,值得临床上进一步推广。Aim To study the effects of mindfulness cognitive behavior group therapy and antidepressant therapy on cognitive function and mental state of patients with depression.Methods 130 patients with depression were selected and randomly divided into control groupand Mindfulness Cognition Group.The control group was given conventional antidepressant treatment,and the Mindfulness Cognition Group was given mindfulness cognitive behavior group treatment on the basis of the control group Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),Simplified Coping Style Questionnaire(SCSQ)and Wisconsin Card Sorting Test(WCST)were used to evaluate the efficacy of bed treatment.Results The effective rate of the Mindfulness Cognition Group was significantly higher than the control group(P<0.05);compared with before treatment,the HAMD and HAMA scores of the two groups after treatment were reduced,and the decline degree of the Mindfulness Cognition Group was significantly greater than that of the control group(P<0.05);the improvement degree of SCSQ score ofMindfulness Cognition Group after treatment was greater than that of the control group(P<0.05)The total number of responses,the number of non persistent errors should be more than that of the control group(P<0.05),and the number of persistent errors should be less than that of the control group(P<0.05).Conclusion Mindfulness cognitive behavior group therapy combined with antidepressants in the treatment of patients with depression can effectively promote the recovery of cognitive function,improve the corresponding way,relieve anxiety and depression of patients,which is worthy of further promotion in clinical practice.

关 键 词：正念认知法 抑郁症 抗抑郁药物 

分 类 号：R749[医药卫生—神经病学与精神病学]