脑干梗死病情进展的相关危险因素分析  

Analysis of risk factors related to the progression of brain stem infarction

作　　者：耿延磊[1] 宋晓文[1] 庄伟 陈金波[1] GENG Yanlei;SONG Xiaowen;ZHUANG Wei;CHEN Jinbo(Department of Neurology,Binzhou Medical University Hospital,Binzhou 256603,Shandong,P.R.China)

机构地区：[1]滨州医学院附属医院神经内科,山东滨州256603

出　　处：《滨州医学院学报》2021年第4期257-260,共4页Journal of Binzhou Medical University

摘　　要：目的探讨脑干梗死进展的危险因素。方法选取确诊的脑干梗死患者173例,分为进展组和未进展组,比较两组的危险因素,并进行多因素logistic回归分析。结果与未进展组比较,进展组吸烟史、糖尿病史、发热、不稳定斑块、血管重度狭窄、延髓梗死的比例及低密度脂蛋白(LDL)水平显著升高,而中脑梗死比例显著降低(P均<0.05)。多因素logistic回归分析显示吸烟史、糖尿病史、发热、不稳定斑块、血管重度狭窄和延髓梗死是脑干梗死进展的独立危险因素,而LDL和中脑梗死与脑干梗死进展无关。结论吸烟史、糖尿病史、发热、不稳定斑块、血管重度狭窄和延髓梗死是脑干梗死进展的独立危险因素,可以显著预测脑干梗死的进展;及时识别上述危险因素并加以有效干预可能会预防脑干梗死患者病情加重。Objective To explore the risk factors for the progression of brainstem infarction.Methods Totally 173 patients with confirmed brainstem infarction were selected and divided into two groups:the progressive group and the unprogressive group.The risk factors of the two groups were compared and multivariate logistic regression analysis was performed.Results Compared with those in the non-progressive group,the proportion of smoking history,diabetes history,fever,unstable plaque,severe vascular stenosis,medulla oblongata infarction and LDL level in the progressive group significantly increased,while the proportion of midbrain infarction significantly decreased(all P<0.05).Multivariate logistic regression analysis showed that smoking history,diabetes history,fever,unstable plaque,severe vascular stenosis and medulla oblongata infarction were independent risk factors for the progression of brainstem infarction,while LDL and midbrain infarction were not associated with the progression of brainstem infarction.Conclusion Smoking history,diabetes history,fever,unstable plaque,severe vascular stenosis and medulla oblongata infarction are independent risk factors for the progression of brainstem infarction,which can significantly predict the progression of brainstem infarction.Timely identification of the above risk factors and effective intervention may prevent the aggravation of patients with brainstem infarction.

关 键 词：脑干梗死 进展性脑梗死 危险因素 

分 类 号：R746[医药卫生—神经病学与精神病学]