弥散张量成像技术在急性缺血性脑卒中的研究进展  

Research progress of diffusion tensor imaging technique in acute ischemic stroke

作　　者：顾楠 谢春明[2] GU Nan;XIE Chun-ming(School of Medicine,Southeast University,Nanjing 210009,China)

机构地区：[1]东南大学医学院,南京210009 [2]东南大学附属中大医院神经内科,南京210009

出　　处：《临床神经病学杂志》2021年第4期314-317,共4页Journal of Clinical Neurology

基　　金：国家自然科学基金面上项目(81671256);天普研究基金(KF201408)。

摘　　要：急性缺血性脑卒中(AIS)是当今危害人类健康的重要疾病。AIS可损害脑白质纤维,导致运动和言语障碍等,因此精准评估脑卒中后白质病变严重程度及其对临床疗效和预后影响至关重要。DTI有助于判断脑白质微观结构损伤情况,近年来成为评估AIS发病时间、严重程度和临床预后等相关指标的研究热点。本文将从DTI的原理、对缺血性脑卒中的诊断及预后预测的价值、现存的挑战等方面进行综述。Acute ischemic stroke(AIS)is a serious disease that endangers human health nowadays.AIS can damage white matter fibers,leading to motor and speech disorders.Therefore,it is crucial to accurately assess the severity of white matter lesions after stroke and its impact on clinical efficacy and prognosis.DTI is helpful to judge the damage of white matter microstructure.In recent years,it has become a research hotspot to assess the onset time,severity and clinical prognosis of AIS.This article reviews the principle of DTI,its value in diagnosis and prognosis prediction after acute ischemic stroke and existing challenges.

关 键 词：DTI 缺血性脑卒中 运动 失语 诊断 预后预测 

分 类 号：R743.3[医药卫生—神经病学与精神病学]