非乳头部位的原发性早期十二指肠癌内镜下切除的安全性与有效性  

Safety and efficacy of endoscopic resection for early primary non-ampullary duodenal cancer

作　　者：董海燕[1] 贾欣永[1] 庞秋萍[1] 张秀娟[1] 王玉龙[2] Dong Haiyan;Jia Xinyong;Pang Qiuping;Zhang Xiujuan;Wang Yulong(Department of Endoscopy,the First Affiliated Hospital of Shandong First Medical University,Ji'nan 250014,China;Department of General Surgery,the First Affiliated Hospital of Shandong First Medical University,Ji'nan 250014,China)

机构地区：[1]山东第一医科大学第一附属医院(山东省千佛山医院)内镜诊疗科,济南250014 [2]山东第一医科大学第一附属医院(山东省千佛山医院)普外中心,济南250014

出　　处：《中华普通外科杂志》2021年第8期604-607,共4页Chinese Journal of General Surgery

摘　　要：目的观察内镜治疗非乳头部位的原发性早期十二指肠癌的安全性与有效性。方法收集2015年1月—2019年12月山东第一医科大学第一附属医院内镜诊疗科诊断并内镜下切除的原发性早期十二指肠癌20例患者的临床资料,评价内镜下切除早期十二指肠癌的临床疗效。结果本组20例患者的21处病变长径为0.3~2.5 cm,平均(0.9±0.5)cm;切除标本大小约1.5~3.5 cm,平均(2.5±0.7)cm。2例患者发生术中穿孔,均成功闭合。术后病理证实21处病变均治愈性切除。随访患者4~42个月,均无复发。结论内镜下治疗原发性早期十二指肠癌安全有效。Objective To evaluate the safety and efficacy of endoscopic resection in the treatment of patients with primary non-ampullary duodenal early cancer.Methods A total of 20 cases with primary non-ampullary duodenal early cancer receiving endoscopic resection were collected from Jan 2015 to Dec 2019 at the Department of Endoscopy,the First Affiliated Hospital of Shandong First Medical University.Results The size of lesions ranged from 0.3-2.5 cm(0.9±0.5)cm.The size of removed membrane samples ranged from 1.5-3.5 cm(2.5±0.7)cm.The edges were all negatiue pathologically.Duodenal perforation occurred in 2 cases,and all were successfully clipped by endoscopy.The follow-up time was from 4-42 months(20.4±11.4)m and no recurrence was found.Conclusion Endoscopic resection is a safe and effective method for primary non-ampullary duodenal early cancer.

关 键 词：十二指肠肿瘤 内窥镜检查 安全性 

分 类 号：R735.31[医药卫生—肿瘤]