A Potential Marker DYF371 for Differentiating Han Population from Non-Han Population in Chinese  

作　　者：Hailun Nan Dejian Lu 

机构地区：[1]Faculty of Forensic Medicine,Zhongshan Medical School,Sun Yat‑Sen University,Guangzhou,China

出　　处：《Journal of Forensic Science and Medicine》2020年第1期1-4,I0001,共5页法庭科学与法医学杂志（英文）

摘　　要：DYF371 locus and single‑nucleotide polymorphisms(SNPs)defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals,including 90 Han population and 52 minorities.In total,37 SNP-short tandem repeat haplotypes were detected.Nine of these 37 haplotypes were unique(24.32%).The gene diversity and discrimination capacity values are 0.8321 and 0.2606,respectively.Furthermore,only five males(5.55%)in the Han samples were determined that they had one copy of allele with SNP T-type and three copies of alleles with SNP C-types,whereas 14 individuals(26.92%)were observed in minorities’samples.The genotype proportion comprising three distinguishing copies of the allele with SNP C-types in Han sample was greatly lower than that in the sample of minorities.Similar results were shown for allele 11C and 10C.Therefore,the alleles of DYF371 with SNP C-type have the potential to differentiate the Han and non-Han Chinese populations.

关 键 词：DYF371 MULTI-COPY multiplex polymerase chain reaction single-nucleotide polymorphism polymorphism-short tandem repeat 

分 类 号：S51[农业科学—作物学]