MULTI-COPY

作品数：14被引量：30H指数：4
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相关作者：朱祯李旭刚常团结曾千春陈松彪更多>>
相关机构：中国科学院遗传与发育生物学研究所北京邮电大学更多>>
相关期刊：《Science China(Life Sciences)》《The Journal of China Universities of Posts and Telecommunications》《Science Bulletin》《Chinese Physics B》更多>>
相关基金：国家自然科学基金国家转基因植物研究与产业化专项国家高技术研究发展计划上海市自然科学基金更多>>
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Improving solubility and copy number of taxadiene synthase to enhance the titer of taxadiene in Yarrowia lipolytica被引量：4
《Synthetic and Systems Biotechnology》2023年第2期331-338,共8页Man Xu Wenliang Xie Zhen Luo Chun-Xiu Li Qiang Hua Jian-He Xu 
supported by the National Key Research and Development Program of China(2019YFA0905000);the National Natural Science Foundation of China(21871085 and 31971380);the Fundamental Research Funds for the Central Universities(222201714026).
Taxadiene is an important precursor for the biosynthesis of highly effective anticancer drug paclitaxel,but its microbial biosynthesis yield is very low.In this study,we employed Yarrowia lipolytica as a microbial hos...
关键词：Taxadiene Yarrowia lipolytica “Push–pull”ostrategy Multi-copy integration Fed-batch fermentation 
Multiplexed site-specific genome engineering in Mycolicibacterium neoaurum by Att/Int system
《Synthetic and Systems Biotechnology》2022年第3期1002-1011,共10页Ke Liu Gui-Hong Lin Kun Liu Yong-Jun Liu Xin-Yi Tao Bei Gao Ming Zhao Dong-Zhi Wei Feng-Qing Wang 
supported by the National Natural Science Foundation of China(No.21776075);the Natural Science Foundation of Shanghai(No.20ZR1415100);the National Key Research and Development Program of China(No.SQ2020YFC210061).
Genomic integration of genes and pathway-sized DNA cassettes is often an indispensable way to construct robust and productive microbial cell factories.For some uncommon microbial hosts,such as Mycolicibacterium and My...
关键词：Site-specific recombination Phage integrase Xer recombinases Mycolicibacterium Multi-copy integration 
The Biological Significance of Multi-copy Regions and Their Impact on Variant Discovery
《Genomics, Proteomics & Bioinformatics》2020年第5期516-524,共9页Jing Sun Yanfang Zhang Minhui Wang Qian Guan Xiujia Yang Jin Xia Ou Mingchen Yan Chengrui Wang Yan Zhang Zhi-Hao Li Chunhong Lan Chen Mao Hong-Wei Zhou Bingtao Hao Zhenhai Zhang 
supported by the National Natural Science Foundation of China(NSFC,Grant No.31771479);Science Fund for Creative Research Groups of the NSFC(Grant No.81521003);Projects of International Cooperation and Exchanges of NSFC(Grant No.61661146004);Municipal Planning Projects of Scientific Technology of Guangdong(Grant No.201804020083);the Science and Technology Program of Guangzhou(Grant No.201400000004);the Natural Science Foundation of Guangdong(Grant No.2015B050501006);the Team Program of Natural Science Foundation of Guangdong(Grant No.2014A030312002);the 1000 Talents Program of China。
Identification of genetic variants via high-throughput sequencing(HTS)technologies has been essential for both fundamental and clinical studies.However,to what extent the genome sequence composition affects variant ca...
关键词：Multi-copy sequence Multi-copy region Genetic study Variant discovery High-throughput sequencing 
Disjoint-Path Routing Mechanism in Mobile Opportunistic Networks
《国际计算机前沿大会会议论文集》2020年第1期368-379,共12页Peiyan Yuan Hao Zhang Xiaoyan Huang 
the National Natural Science Foundation of China under Grants U1804164,61902112 and U1404602;in part by the Science and Technology Foundation of Henan Educational Committee under Grants 19A510015,20A520019,20A520020.
The prevalent multi-copy routing algorithms in mobile opportunistic networks(MONs)easily cause network congestion.This paper introduces a disjoint-path(DP)routing algorithm,where each node can only transmit packets on...
关键词：MULTI-COPY Disjoint-path Mobile opportunistic networks ROUTING Continuous time Markov chain 
A Potential Marker DYF371 for Differentiating Han Population from Non-Han Population in Chinese
《Journal of Forensic Science and Medicine》2020年第1期1-4,I0001,共5页Hailun Nan Dejian Lu 
DYF371 locus and single‑nucleotide polymorphisms(SNPs)defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals,including 90 Han population and 52 minorities.In total,37 SNP...
关键词：DYF371 MULTI-COPY multiplex polymerase chain reaction single-nucleotide polymorphism polymorphism-short tandem repeat 
Metabolic engineering of Streptomyces coelicolor for enhanced prodigiosins (RED) production被引量：7
《Science China(Life Sciences)》2017年第9期948-957,共10页Panpan Liu Hong Zhu Guosong Zheng Weihong Jiang Yinhua Lu 
supported by the National Natural Science Foundation of China(31430004,31421061,31630003,31370081 and 31570072);the Science and Technology Commission of Shanghai Municipality(16490712100)
Bacterial prodigiosins are red-colored secondary metabolites with multiple activities,such as anticancer,antimalarial and immunosuppressive,which hold great potential for medical applications.In this study,dramaticall...
关键词：Streptomyces coelicolor prodigiosins metabolic engineering multi-copy integration 
Multi-copy entanglement purification with practical spontaneous parametric down conversion sources
《Chinese Physics B》2017年第6期53-60,共8页张帅帅 祁舒 周澜 盛宇波 
supported by the National Natural Science Foundation of China(Grant Nos.11474168 and 61401222);the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20151502);the Qing Lan Project in Jiangsu Province,China;a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions,China
Entanglement purification is to distill the high quality entanglement from the low quality entanglement with local operations and classical communications. It is one of the key technologies in long-distance quantum co...
关键词：quantum communication ENTANGLEMENT entanglement purification 
Fast multi-copy entanglement purification with linear optics
《Chinese Physics B》2015年第12期232-237,共6页蔡春 周澜 盛宇波 
Project supported by the National Natural Science Foundation of China(Grant Nos.11474168 and 61401222);the Qing Lan Project of Jiangsu Province;China;the STITP Project in Nanjing University of Posts and Telecommunications;the Natural Science Foundation of Jiangsu Province;China(Grant No.BK20151502);the Natural Science Foundation of the Jiangsu Higher Education Institutions(Grant No.15KJA120002);the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions;China
We describe an entanglement purification protocol for a polarization Bell state. Different from the previous protocols,it does not require the controlled-not gate, and only uses linear optical elements to complete the...
关键词：quantum computation entanglement purification ENTANGLEMENT 
Message redundancy removal of multi-copy routing in delay tolerant MANET被引量：2
《The Journal of China Universities of Posts and Telecommunications》2011年第1期42-48,共7页YU Hai-zheng MA Jian-feng BIAN Hong 
supported by the Hi-Tech Research and Development Program of China (2007AA01Z429,2007AA01Z405);the National Natural Science Foundation of China (60702059,60872041,11061035)
This article puts forward a new scheme to control message redundancy efficiently in delay tolerant mobile Ad-hoc networks （MANET）. The class of networks generally lacks end-to-end connectivity. In order to improve t...
关键词：delay tolerant networks mobile Ad-hoc networks message routing redundancy removal 
Expression of lignin peroxidase H2 from Phanerochaete chrysosporium by multi-copy recombinant Pichia strain被引量：4
《Journal of Environmental Sciences》2009年第2期218-222,共5页WANG Wei,WEN Xianghua Department of Environmental Science and Engineering,Tsinghua University,Beijing 100084,China. 
supported by the National Natural Science Foundation of China (No. 20577028).
The lipH2 gene, encoding the expression of lignin peroxidase, was cloned from Phanerochaete chrysosporium BKM-F-1767 and expressed in Pichia pastoris X-33, a yeast. The cDNA of LiPH2 was generated from total RNA extra...
关键词：heterologous expression lignin peroxidase Pichia pastoris 
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