DTC患者经^(131)I治疗后唾液腺损伤的评价及预防  

Evaluation and prevention of salivary gland injury in DTC patients after ^(131)I therapy

作　　者：尚康康 程兵[1] Shang Kangkang;Cheng Bing(Department of Nuclear Medicine,the First Affiliated Hospital of Zhengzhou University,Henan Medical Key Laboratory of Molecular Imaging,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院核医学科,河南省分子影像医学重点实验室,450052

出　　处：《国际放射医学核医学杂志》2021年第5期332-337,共6页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：河南省科技攻关项目(172102310259)。

摘　　要：^(131)I治疗是分化型甲状腺癌(DTC)患者术后常规的辅助治疗,可有效降低疾病的复发率,延长患者的生存期,并对预后起到积极作用。但^(131)I在治疗原发病灶的同时,也会对人体的局部正常组织(如唾液腺)造成损伤,影响患者的生活质量。目前,DTC患者经^(131)I治疗后的唾液腺损伤已经引起了临床上的广泛关注,笔者从唾液腺损伤的评价及预防两方面展开综述。^(131)I therapy is a routine adjuvant therapy for patients with differentiated thyroid carcinoma(DTC)after operation,which can effectively reduce the recurrence rate of the disease,prolong the survival period of patients,and play a positive role in the prognosis.However,when ^(131)I treats the primary lesion,it will also cause damage to local tissues of the human body(such as the salivary gland)and affect the life quality of patients.At present,salivary gland injury in DTC patients after ^(131)I therapy has caused widespread clinical concern.This review focuses on the evaluation and prevention of salivary gland injury.

关 键 词：甲状腺肿瘤 碘放射性同位素 辐射损伤 唾液腺 

分 类 号：R736.1[医药卫生—肿瘤] R730.55[医药卫生—临床医学]