多发性基底细胞癌6例临床与皮肤镜特征分析  

Clinical and dermoscopic features of 6 patients with multiple basal cell carcinoma

作　　者：崔莉[1] 蒋洁[2] 王希艳[1] 杜青芳 尚亚洲 CUI Li;JIANG Jie;WANG Xi-yan(Department of Dermatology,Shaanxi Provincial People's Hospital,Xi'an 710068,China)

机构地区：[1]陕西省人民医院皮肤科,西安710068 [2]陕西省人民医院肿瘤内科

出　　处：《实用皮肤病学杂志》2021年第3期152-155,共4页Journal of Practical Dermatology

基　　金：陕西省中医药管理局科研课题任务书项目(2019-ZZ-JC039)。

摘　　要：目的探讨多发性基底细胞癌的临床及皮肤镜特征。方法回顾性分析经皮肤镜诊断且组织病理确诊为多发性基底细胞癌的6例21处皮损其临床及皮肤镜特征。结果6例多发性基底细胞癌患者的平均年龄54.2岁,平均病程8.25年,男女比例1:1。21处皮损中临床分型为结节溃疡型9处、色素型7处、浅表型5处。多发性基底细胞癌皮肤镜特征按出现频率依次为:蓝灰色卵圆形巢(85.7%)、多发性蓝灰色小球(71.4%)、分支状血管(61.9%)、分支状毛细血管扩张(61.9%)、溃疡(47.6%)、无结构区(47.6%)等。结论多发性基底细胞癌临床少见,通过对其临床及皮肤镜特征的综合分析,意在提高临床医生对该病的认识,有助于精准诊断和治疗。Objective To investigate the clinical and dermoscopic features of patients with multiple basal cell carcinoma(BCC). Methods The clinical and dermoscopic features were analyzed by dermoscopy and biopsy in 21 lesions from 6 patients with multiple BCC. Result The average age of the 6 patients with multiple BCC was 54.2 years old and the average course was 8.25 years. The ratio of male to female was 1:1. Among the 21 lesions, there were 9 lesions belonging to nodular ulcerative variant, as well as 7 pigmented variant and 5 superficial variant. The main dermoscopic features of BCC were large blue, gray ovoid nests(85.7%), brown globules/dots(71.4%), branching vessels(61.9%), telangiectactic vessels(61.9%), ulceration(47.6%), and featureless areas(47.6%). Conclusion Multiple basal cell carcinoma is rare in clinic, thus comprehensively analysis of its clinical and dermoscopic characteristics may be helpful for improving the understanding, accurate diagnosis and treatment of the disease.

关 键 词：癌 基底细胞 皮肤镜 诊断 

分 类 号：R739.5[医药卫生—肿瘤]