补体系统在淋巴瘤中的作用研究进展  

Progress of the role of complement system in lymphoma

作　　者：涂冬云 桑威 徐开林 Tu Dongyun;Sang Wei;Xu Kailin(Department of Hematology,Affiliated Hospital of Xuzhou Medical University Cell Research and Transformation Center,Affiliated Hospital of Xuzhou Medical University Institute of Hematology,Xuzhou Medical University,Xuzhou 221000,China)

机构地区：[1]徐州医科大学血液病研究所,徐州医科大学附属医院细胞研究和转化医学中心,徐州医科大学附属医院血液科,江苏徐州221000

出　　处：《白血病．淋巴瘤》2021年第7期444-448,共5页Journal of Leukemia & Lymphoma

基　　金：江苏省青年医学重点人才(QNRC2016791);江苏省自然科学基金(BK20171181);江苏省科技厅社会发展重点项目(BE2019638)。

摘　　要：补体系统是一个具有精细调控机制的蛋白质反应系统,是机体固有免疫和适应性免疫的重要组成部分。补体成分异常、过度活化等功能障碍与淋巴瘤的发生、发展和免疫逃逸密切相关。此外对于临床治疗,尤其免疫治疗具有一定相关性。现就补体系统在淋巴瘤发生及治疗中的作用进行综述。The complement system is a protein response system with a precise regulation mechanism,and an important part of the body's innate and adaptive immunity.Abnormal complement components,excessive activation and other functional disorders are closely related to the development and progression of lymphoma and immune escape.In addition,the complement system has a certain relevance to clinical treatment,especially immunotherapy.This paper reviews the role of complement system in the occurrence and treatment of lymphoma.

关 键 词：淋巴瘤 补体系统蛋白质类 免疫疗法 治疗应用 

分 类 号：R733.1[医药卫生—肿瘤]