富血小板纤维蛋白结合引导骨再生技术在牙周病患者颌骨缺损中精细位点重建中的价值分析  

Analysis of the Value of Platelet-rich Fibrin Combined with Guided Bone Regeneration Technique in Fine Site Reconstruction of Jaw Defects in Patients with Periodontal Disease

作　　者：董潇 曲行舟[2] DONG Xiao;QU Xingzhou(Department of Stomatology,Shanxian Central Hospital,Shanxian,Shandong Province,274300 China;Department of Oral and Maxillofacial Head and Neck Oncology,the Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai,200011 China)

机构地区：[1]单县中心医院口腔科,山东单县274300 [2]上海交通大学医学院附属第九人民医院口腔颌面头颈肿瘤科,上海200011

出　　处：《世界复合医学》2021年第6期77-80,95,共5页World Journal of Complex Medicine

基　　金：上海交通大学“医工交叉研究基金”项目(YG2017MS02)。

摘　　要：目的研究出现颌骨缺损问题的牙周病患者在精细位点重建过程中应用富血小板纤维蛋白结合引导骨再生技术的临床效果。方法选择2018年6月—2020年6月在单县中心医院口腔科接受治疗的88例出现颌骨缺损问题的牙周病患者,根据治疗方式的不同分成对照组和治疗组,单纯采用引导骨再生技术进行精细位点重建的44例患者为对照组,采用富血小板纤维蛋白结合引导骨再生技术进行精细位点重建的44例患者为治疗组。对比两组研究对象治疗总有效率、不良反应、治疗前后牙周状态指标水平、牙周病症状消失、牙齿功能恢复正常、治疗总时间。结果治疗组总有效率为90.9%,对照组为70.5%,差异有统计学意义(χ^(2)=5.906,P<0.05);不良反应仅出现2例,少于对照组的9例,组间差异有统计学意义(χ^(2)=5.090,P<0.05);治疗前两组菌斑指数、龈沟出血指数、探针出血指数、牙周探针深度差异无统计学意义(P>0.05);治疗后治疗组的菌斑指数、龈沟出血指数、探针出血指数、牙周探针深度均优于对照组,差异有统计学意义(P<0.05)。治疗组牙周病症状消失、牙齿功能恢复正常、治疗总时间短于对照组,差异有统计学意义(P<0.05)。结论出现颌骨缺损问题的牙周病患者在精细位点重建过程中应用富血小板纤维蛋白结合引导骨再生技术,减少不良反应,缩短牙周病症状消失、牙齿功能恢复正常、治疗总时间,改善牙周状态指标,使病情治疗总有效率提高。Objective To study the clinical effect of platelet-rich fibrin combined with guided bone regeneration in the process of fine site reconstruction in periodontal patients with jaw defects.Methods Eighty-eight periodontal patients with jaw defects who were treated in the department of stomatology of Shanxian Central Hospital from June 2018 to June 2020 were selected.They were divided into control group and treatment group according to different treatment methods,and guided bones were used alone for forty-four patients who performed fine site reconstruction with regeneration technology as the control group,and 44 patients who used platelet-rich fibrin binding guided bone regeneration technology for fine site reconstruction as the treatment group.The total effective rate of treatment,adverse reactions,index levels of periodontal status before and after treatment,disappearance of periodontal disease symptoms,restoration of tooth function to normal,and total treatment time were compared between the two groups of subjects.Results The total effective rate of treatment group was 90.9%,and that of the control group was 70.5%,and the difference was statistically significant(χ^(2)=5.906,P<0.05);only 2 cases of adverse reactions occurred,which was less than the 9 cases in the control group,and the difference was statistically significant(χ^(2)=5.090,P<0.05);there was no statistically significant difference between the two groups of plaque index,gingival sulcus bleeding index,probe bleeding index,and periodontal probe depth before treatment(P>0.05);the plaque index,sulcus bleeding index,probe bleeding index,and periodontal probe depth of the treatment group after treatment were all better than the control group,and the difference was statistically significant(P<0.05).The symptoms of periodontal disease disappeared,the tooth function returned to normal,and the total treatment time in the treatment group was shorter than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Patients with

关 键 词：颌骨缺损 精细位点 富血小板纤维蛋白 引导骨再生 

分 类 号：R782.4[医药卫生—口腔医学] R781.4[医药卫生—临床医学]