原发性小肠肿瘤临床特征分析  

Analysis of Clinical Features of Primary Small Bowel Tumors

作　　者：刘钟城 龙美春 肖志明[1] 郭勤 LIU Zhong-cheng;LONG Mei-chun;XIAO Zhi-ming;GUO Qin(Department of Gastroenterology,Third Xiangya Hospital,Central South University,Changsha 410013,Hunan,China;Department of Gastroenterology,the Sixth Affiliated Hospital of Sun Yat-sen University,Guangzhou 510655,Guangdong,China)

机构地区：[1]中南大学湘雅三医院消化内科,湖南长沙410013 [2]中山大学附属第六医院消化内科,广东广州510655

出　　处：《医学信息》2021年第18期122-125,共4页Journal of Medical Information

摘　　要：目的探讨原发性小肠肿瘤的临床特点。方法收集2015年9月-2020年9月于中南大学湘雅三医院经病理确诊的131例原发性小肠肿瘤患者的临床资料,分析原发性小肠肿瘤的临床特点。结果131例患者中良性肿瘤22例,以腺瘤最常见;恶性肿瘤109例,以恶性间质瘤最常见;肿瘤位置位于十二指肠者25例(19.10%),位于空肠者55例(42.00%),位于回肠者37例(28.20%),十二指肠及空肠均有者2例(1.50%),空肠及回肠均有者12例(9.20%);患者的首发临床表现以腹痛(46.60%)最为常见,其次依次是腹胀(25.20%)及黑便(27.50%);良恶性小肠肿瘤患者平均HGB、Alb含量比较,差异无统计学意义(P>0.05);AFP阳性2.17%,糖类抗原CA199阳性8.60%,CEA阳性11.46%,CA125阳性13.70%,铁蛋白阳性7.32%,17例检测CEA的腺癌患者,有41.18%升高,16例腺癌患者检测CA199,37.50%升高;CTE及双气囊小肠镜检出率达100.00%。结论原发性小肠肿瘤以恶性多见,最常见的病理类型是恶性间质瘤,发病部位以空肠多见。CTE及双气囊小肠镜可明显提高原发性小肠肿瘤的检出率。Objective To explore the clinical characteristics of primary small bowel tumors.Methods The clinical data of 131 patients with primary small bowel tumors diagnosed pathologically in the Third Xiangya Hospital of Central South University from September 2015 to September 2020 were collected,and the clinical characteristics of primary small bowel tumors were analyzed.Results Among the 131 patients,22 were benign tumors,with adenomas being the most common;malignant tumors were 109,with malignant stromal tumors being the most common;The tumor was located in the duodenum in 25 cases(19.10%),in the jejunum in 55 cases(42.00%),in the ileum in 37 cases(28.20%),and in the duodenum and jejunum in 2 cases(1.50%),there were 12 cases(9.20%)in both jejunum and ileum;The first clinical manifestations of patients were abdominal pain(46.60%),followed by abdominal distension(25.20%)and melena(27.50%);There was no significant difference in the average hemoglobin and albumin content of patients with benign and malignant small bowel tumors(P>0.05);AFP positive 2.17%,carbohydrate antigen CA199 positive 8.60%,CEA positive 11.46%,CA125 positive 13.70%,ferritin positive7.32%,In 17 adenocarcinoma patients with carcinoembryonic antigen,41.18%increased,and 16 adenocarcinoma patients detected CA199,37.50%increased;The detection rate of CTE and double-balloon enteroscopy reached 100.00%.Conclusion Primary small bowel tumors are more common in malignancy.The most common pathological type is malignant stromal tumors.The most common pathological site is the jejunum.CTE and double-balloon enteroscopy can significantly improve the detection rate of primary small bowel tumors.

关 键 词：原发性小肠肿瘤 双气囊小肠镜 恶性间质瘤 

分 类 号：R735[医药卫生—肿瘤]