HPLC-MS/MS法测定食品塑料包装制品中8种防老剂  

Determination of Residues of Eight Antioxidants in Food Plastic Packaging Products by High Performance Liquid Chromatography-Tandem Mass Spectrometry

作　　者：郑燕燕[1] 蒋明峰 张悦[1] 谢晓娟 黎永乐[1] ZHENG Yan-yan;JIANG Ming-feng;ZHANG Yue;XIE Xiao-juan;LI Yong-le(Shenzhen Academy of Metrology&Quality Inspection,Shenzheng 518131,China)

机构地区：[1]深圳市计量质量检测研究院,广东深圳518131

出　　处：《包装工程》2021年第17期1-9,共9页Packaging Engineering

基　　金：国家重点研发计划(2018YFC1603201,2018YFC1603200);广东省市场监督管理局科技项目(2020CS04)。

摘　　要：目的探究防老剂在食品塑料包装制品中的使用情况,以期建立食品塑料包装制品中防老剂(N-苯基-2-萘胺、1-萘氨基苯、乙氧基喹啉、橡胶防老剂DTPD、橡胶防老剂4010NA、防老剂ODA、防老剂H、N,N′-二苯基对苯二胺)残留量的高效液相色谱-串联质谱(HPLC-MS/MS)检测方法。方法样品经三氯甲烷和甲醇提取、浓缩,甲醇复溶后,用高效液相色谱-串联质谱测定,外标法定量。结果8种防老剂残留量为10.0~200.0μg/L时线性关系良好(相关系数R2>0.999),定量下限为5.0μg/kg。在10,20,100μg/kg 3个加标水平下,8种防老剂的加标平均回收率为81%~116%,相对标准偏差小于等于3.77。结论文中方法准确、高效、简单,可用于食品塑料包装制品中8种防老剂残留量定性定量测定。Through exploring the use of antioxidant in food plastic packaging products,an analytical method of de-termining residues of eight antioxidants(N-Phenyl-2-naphthylamine,N-Phenyl-1-naphthylamine,Ethoxyquin,1,4-Benzenediamine,N-Isopropyl-N'-phenyl-1,4-phenylenediamine,Dioctyldiphenylamine,1,4-Dianilinobenzene,N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine)by HPLC-MS/MS was established.The samples were extracted by chloroform and methanol,then concentrated and redissolved by methanol.The extract was analyzed by HPLC-MS/MS and quantified by external standard method.The linear ranges of eight compounds ranging from 10.0 to 200.0μg/L with correlation coefficients(R2)more than 0.999,and the detection lower limits were 5.0μg/kg.The average recoveries of eight compounds were ranging from 81%to 116%at three spiked concentration levels of 10,20 and 100μg/kg with rela-tive standard deviations not more than 3.77.The method is accurate,simple and efficient,and can be used for qualitative and quantitative determination of residues of eight antioxidants in food plastic packaging products.

关 键 词：高效液相色谱-串联质谱法 塑料制品 防老剂 残留量 

分 类 号：TS206[轻工技术与工程—食品科学] TQ320.77[轻工技术与工程—食品科学与工程]