Serrated lesions:A challenging enemy  

作　　者：Alexa Trovato Alla Turshudzhyan Micheal Tadros 

机构地区：[1]Albany Medical College,Albany,NY 12208,United States [2]Department of Medicine,University of Connecticut,School of Medicine,Farmingdale,CT 06032,United States [3]Department of Gastroenterology,Albany Medical Center,Albany,NY 12208,United States

出　　处：《World Journal of Gastroenterology》2021年第34期5625-5629,共5页世界胃肠病学杂志（英文版）

摘　　要：The serrated pathway accounts for 30%-35%of colorectal cancer(CRC).Unlike hyperplastic polyps,both sessile serrated lesions(SSLs)and traditional serrated adenomas are premalignant lesions,yet SSLs are considered to be the principal serrated precursor of CRCs.Serrated lesions represent a challenge in detection,classification,and removal–contributing to post-colonoscopy cancer.Therefore,it is of the utmost importance to characterize these lesions properly to ensure complete removal.A retrospective cohort study developed a diagnostic scoring system for SSLs to facilitate their detection endoscopically and subsequent removal.From the study,it can be ascertained that both indistinct border and mucus cap are essential in both recognizing and diagnosing serrated lesions.The proximal colon poses technical challenges for some endoscopists,which is why high-quality colonoscopy plays such an important role.The indistinct border of some SSLs poses another challenge due to difficult complete resection.Overall,it is imperative that gastroenterologists use the key features of mucus cap,indistinct borders,and size of at least five millimeters along with a high-quality colonoscopy and a good bowel preparation to improve the SSL detection rate.

关 键 词：Sessile serrated lesions COLONOSCOPY POLYPS Colorectal cancer screening Hyperplastic polyps Traditional serrated adenomas 

分 类 号：R735.34[医药卫生—肿瘤]