Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin  

作　　者：Yao Zhou Diyin Li Jianhua Luo Aizhong Chen Xingxinq Li Zhenrui Pan Li Wan Liuqing He Danyang Li Yanyan Li Min Dong Liang Tao 

机构地区：[1]Key Laboratory of Structural Biology of Zhejiang Province,School of Life Sciences,Westlake University,Hangzhou,Zhejiang,China [2]Center for Infectious Disease Research,Westlake Laboratory of Life Sciences and Biomedicine,Hangzhou,Zhejiang,China [3]Institute of Basic Medical Sciences,Westlake Institute for Advanced Study,Hangzhou,Zhejiang,China [4]Department of Urology,Boston Children's Hospital,Boston,MA,USA [5]Department of Surgery and Department of Microbiology,Harvard Medical School,Boston,MA,USA

出　　处：《Cell Research》2021年第8期935-938,共4页细胞研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(31970129 and 31800128 to L.T.);Zhejiang Provincial Natural Science Foundation of China(LR20C010001 to L.T.and LR20C050001 to Y.L.).L.T.;support from Westlake Education Foundation and Tencent Foundation.

摘　　要：Dear Editor,Clostridium novyi(C.novyi)is a spore-forming anaerobic bacterium and opportunistic pathogen causing severe infectious diseases in humans and animals including gas gangrene,myositis,necrotic hepatitis,and sepsis.

关 键 词：media ANAEROBIC LIPOPROTEIN 

分 类 号：R37[医药卫生—病原生物学]