Analysis of ocular structural parameters and higher-order aberrations in Chinese children with myopia  

作　　者：Xue Li Qi Hu Qian-Ru Wang Zi-Qing Feng Fan Yang Chun-Yu Du 

机构地区：[1]Department of Ophthalmology,The Center of Optometry of The First Affiliated Hospital of Harbin Medical University,Harbin 150000,Heilongjiang Province,China [2]Department of Ophthalmology,The Second Hospital of Shanxi Medical University,Taiyuan 030000,Shanxi Province,China [3]Department of Ophthalmology,Zhongshan Ophthalmic Center,State Key Laboratory of Ophthalmology,Sun Yat-Sen University,Guangzhou 510000,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2021年第27期8035-8043,共9页世界临床病例杂志

基　　金：Supported by Scientific Research Project of Heilongjiang Health Commission,China,No.2020-141.

摘　　要：BACKGROUND Myopia and high myopia are global public health concerns.Patients with high myopia account for 0.5%-5.0%of the global population.AIM To examine diopters,axial length(AL),higher-order aberrations,and other ocular parameters in Chinese children with myopia,to analyze the influence of structural parameters associated with myopia on visual quality,and to provide a theoretical basis for the prevention and treatment of childhood myopia and high myopia.METHODS This study included 195 children aged 6–17 years with myopia.The AL was measured with an ultrasonic ophthalmic diagnostic instrument,and the aberrations,corneal curvature(minimum K1,maximum K2,and average Km),central corneal thickness,anterior chamber depth,and anterior chamber angle were measured using a Sirius three-dimensional anterior segment analyzer.Using a standard formula,the corneal radius of curvature R(337.3/Km)and AL/R values were obtained.RESULTS The diopter of high myopia compared with low-middle myopia was correlated with age and AL(r=-0.336,-0.405,P<0.001),and AL of high myopia was negatively correlated with K1,K2,and Km(r=-0.673,-0.661,and-0.680,respectively;P<0.001),and positively correlated with age and the anterior chamber depth(r=0.214 and 0.275,respectively;P<0.05).AL/R was more closely related to diopter than AL in children with myopia,and 94.4%of children with myopia had an AL/R of>3.00.CONCLUSION The ocular structural parameters of children change because of different diopters.AL/R is more specific and sensitive than AL in evaluating the refractive status of myopia in children.An AL/R of>3.00 may be used as a specific index of myopia in children.There are differences in AL/R between high myopia and low-middle myopia,which can be used for the classification of ametropia.The degree of myopia has a certain influence on higher-order aberrations.

关 键 词：MYOPIA Higher-order aberrations DIOPTER Axial length Cornea radius of curvature 

分 类 号：R778.11[医药卫生—眼科]