MR弥散张量成像及弥散张量纤维束示踪成像在不同级别脑胶质瘤诊断中的应用  

The Application of DTI and DTT in the Diagnosis of Different Grades of Gliomas

作　　者：万正国[1] 贾雯 孙源源 吕晓清 孟凯龙[1] WAN Zhengguo;JIA Wen;SUN Yuanyuan;LV Xiaoqing;MENG Kailong(CT,MR Room,Handan First Hospital,Handan 056000,Hebei,P.R.China;Clinical School of Hebei University of Engineering,Handan 056000,Hebei,P.R.China)

机构地区：[1]邯郸市第一医院CT、MR室,河北邯郸056000 [2]河北工程大学临床医学院,河北邯郸056000

出　　处：《影像科学与光化学》2021年第5期663-666,共4页Imaging Science and Photochemistry

摘　　要：本文探讨不同级别脑胶质瘤诊断中应用MR弥散张量成像(DTI)及弥散张量纤维束示踪成像(DTT)的价值。选取脑胶质瘤患者84例,比较低级别和高级别脑胶质瘤DTI、DTT参数差异。实验结果显示:高级别瘤周白质纤维束破坏比例明显高于低级别(P<0.05);高级别病灶实质区部分各向异性(FA)值明显高于低级别脑胶质瘤(P<0.05),而表观扩散系数(ADC)值明显低于低级别(P<0.05);高级别瘤周水肿区纤维密度指数(FDi)值明显低于低级别(P<0.05);瘤周白质纤维束破坏,病灶实质区FA值和ADC值,瘤周水肿区FDi值鉴别诊断高级别脑胶质瘤的ROC曲线下面积分别为0.857、0.877、0.965和0.828(P<0.05)。研究证实:同级别脑胶质瘤中,DTI及DTT参数有所差异,在鉴别诊断中有一定应用价值。The purpose of this study was to investigate the value of MR diffusion tensor imaging(DTI)and diffusion tensor tractography(DTT)in the diagnosis of glioma of different grade.84 patients with glioma were selected,the DTI and DTT parameters of low grade and high grade gliomas were compared.The experimental results showed that the damage rate of peritumor white matter fiber bundle in high-grade was significantly higher than that in low-grade(P<0.05).The fractional anisotropy(FA)value of focal parenchymal area in high-grade was significantly higher than that of the low-grade(P<0.05),and the apparent diffusion coefficient(ADC)value was significantly lower than that of the low-grade(P<0.05).The value of fiber density index(FDi)in the peritumor edema area of high-grade was(0.53±0.08),which was significantly lower than that of low-grade(P<0.05).The area under ROC curve of peritumor white matter fiber bundle destruction,FA value and ADC value of lesion parenchyma area,and FDi value of peritumor edema area in differential diagnosis of high grade were 0.857,0.877,0.965 and 0.828,respectively(P<0.05).This study confirmed that:DTI and DTT parameters are different in different grades of glioma,which has certain application value in differential diagnosis.

关 键 词：MR弥散张量成像 弥散张量纤维束示踪成像 脑胶质瘤 诊断价值 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]